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total: 64 pages (4): 1 2 3 4 > Zierhut M., Rammensee H., Streilein W. Informa Healthcare; 2007; ISBN: 0849390206 Book Description: In recent years the importance of antigen-presenting cells and their influence on the eyes has been elucidated. We have learned that nearly every structure of the eye harbors these cells, yet they differ in their activities and thus in the ways in which they protect against - or participate in - diseases of the eye. Antigen-Presenting Cells and the Eye summarizes current knowledge about ACPs in general, and their role in the eye, in particular. Laboratory Companion Ed. Gibson I. Wiley-VCH; 1997; pp.92; ISBN: 352730889X http://www.wiley-vch.de/publish/en/books/bySubjectLS00/ISBN3-527-30889-X<br />http://www3.interscience.wiley.com/cgi-bin/bookhome/119228127 Short description This laboratory companion provides detailed information on the potential, advantages and limitations of this methodology. It presents strategies for choosing targets and delivery systems, allowing selection of the optimum methodology for achieving experimental success with any human or other biological system. For researchers, technicians and advanced graduates in experimental medicine, molecular and cell biology. Review “…recommended for researchers involved in drug discovery.” (The Biotech Journal, April/May 2003) Product Description Antisense and ribozymes have a relatively short yet successful history as research tools in gene expression studies, and thus are considered as having high potential reagents in treating viral infections and cancer. This laboratory companion provides detailed information on the potential, advantages and limitations of this methodology. It critically discusses potential pitfalls, presents strategies for choosing targets and delivery systems, so as to allow the selection of the optimum methodology for achieving fast and reliable experimental success with any human or other biological system. For researchers, technicians and advanced graduates in experimental medicine, molecular and cell biology. CODE http://rapidshare.com/files/132650773/ribozyme.rar Thnx to gigapedia Ed. Crooke S.T. CRC Press; 2007; pp.848; ISBN: 0849387965 http://www.crcpress.com/shopping_cart/products/product_detail.asp?isbn=9780849387968
Divided into five parts, the book begins with a thorough introduction to the mechanism of antisense drug action including the RNase H mechanism, small RNA silencing pathways, and the potential therapeutics of splice switching oligonucleotides. Leading researchers demonstrate the basics of oligonucleotide therapeutics in part two by delineating medicinal chemistry, pharmacokinetics, and delivery routes such as liposomal formulations for nucleic acid delivery. Part three details hybridization based drugs and considers the dramatic advances represented by 2′ methoxyethyl chimeric antisense inhibitors and duplex RNA drugs. Other chemical classes of drugs and mechanisms of action are described in part four with further discussions on improving the second generation antisense drugs. The final part delves deeply into therapeutic applications. Contributing authors examine the potential of antisense drugs for the alleviation of cardiovascular diseases, metabolic diseases, inflammatory diseases, cancer, neurological disorders, and immune modulation. Presenting a highly detailed, lucid discussion of the remarkable advances in the field, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition provides the platform for researchers to continue to aggressively pursue the great opportunity represented by this exciting technology. CODE http://ifile.it/65k2h7/crook0849387965.rar or http://rapidshare.com/files/56358907/Crook0849387965.rar Thnx to gigapedia Methods in Molecular Medicine book106 Ed. Phillips M.I. Humana Press; 2005; pp.344; ISBN: 1588292053 http://springer.com/978-1-58829-205-6 A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs. Written for: Pharmacologists, pathologists, and biomedical researchers CODE http://ifile.it/jhkbst/phi_ast2emmm.rar or http://rapidshare.com/files/36302972/Antisense_Therapeutics_2nd_ed_1588292053.rar Thnx to gigapedia Methods in Molecular Biology book282 Ed. Brady J.M. Humana Press; 2004; pp.320; ISBN: 0896038734 A collection of cutting-edge techniques for detecting and quantifying apoptosis, understanding its biochemistry, and for identifying the genes and proteins that regulate and carry it out. Described in step-by-step detail, these readily reproducible methods range from flow cytometry and immunohistochemical procedures to kinase activity assays, yeast two-hybrid screening, and the cloning of novel genes by differential expression. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Apoptosis Methods and Protocols constitutes a key technical reference to the significant methodologies used in the field, as well as offering novice and experienced researchers alike powerful tools to illuminate the phenomenon of programmed cell death. Los M., Gibson S.B. Springer-Verlag; 2005; ISBN: 0387233849 Book Description: As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer. Ed. Kirschenbaum D.M. Springer-Verlag; 1972; pp.319; ISBN: 159124708X, 0306651599 The spectra in this book provide samples of these subtle spectral differences and permit comparisons to be made. This volume should prove useful to a large and varied group including the student who wants to know what a protein spectrum looks like, the researcher who would like to know about the "shift to the red" on removing nucleotide contaminants from a protein, and the analyst seeking to learn where the isosbestic point of a protein in acid and alkali solutions is located. Whitman, Goodfellow, Mpfer, Busse, Trujillo, Ludwig, Suzuki, Parte Springer-Verlag; 2012; pp.1750; ISBN: 0387682334 Dear colleagues! Can you help me to find this book? Looking forward for your help. Thank you in advance! New Comprehensive Biochemistry book35 Ed. Vance D.E., Vance J. Elsevier Science; 2002; pp.620; ISBN: 044482359X New Comprehensive Biochemistry, Volume 36: Biochemistry of Lipids, Lipoproteins and Membranes, Fourth Edition provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances. Pevsner J. John Wiley & Sons; 2003; pp.792; ISBN: 0471210048 Wley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science. Rosenberg A. Springer-Verlag; 1995; pp.394; ISBN: 0306449749 Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables. Gautham N., Pattabhi V. Kluwer Academic Publishers; 2002; pp.253; ISBN: 0306475200, 1402002181 Biophysics, being an interdisciplinary topic, is of great importance in modern biology. This book addresses the needs of biologists, biochemists, and medical biophysicists for an introduction to the subject. The text is based on a one-semester course offered to graduate students of life sciences, and covers a wide range of topics from quantum mechanics to pre-biotic evolution. To understand the topics, only basic school level mathematics is required. The first chapter introduces and refreshes the reader's knowledge of physics and chemistry. The next chapters cover various physico-chemical techniques used to study biomolecular structures, followed by treatments of spectroscopy, microscopy, diffraction, and computational techniques. X-ray crystallography and NMR are dealt with in greater detail. The latter half of the book covers results obtained from applications of the above techniques. Some of the other topics dealt with are energy pathways, biomechanics, and neuro-biophysics. 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Saunders (now a part of Elsevier Science) ; 2000; pp.553; ISBN: 0721682332 The 5th Edition of this comprehensive title continues the tradition of delivering an accessible, engaging, and current introduction to this essential subject. The authors describe the principles of basic and applied immunology in a concise, straightforward manner, while incorporating the most up-to-date information. Over 400 illustrations help readers quickly and easily grasp key concepts. The entire text has been revised and includes new information about the organization of lymphoid organs and the mechanisms of innate immunity. Wikipedia is a platform where anyone can create or compose their account, publish articles, and even edit the pages; before getting approved by Wikipedia, people are supposed to edit seven articles already on Wikipedia. Many people take help from professional writers and editors to do their projects and hire them, offering payment for their service. Wolfgang K. Thieme Medical Publishers; 2003; pp.542; ISBN: 3135624048 Pervye tri stranicy o izdanii This volume features outstanding histologic and electron microscopic illustrations and is an ideal companion to any textbook of histology and microscopic anatomy. It features numerous tables of differential diagnosis. Specimens can be quickly identified by their specific features. This 11th edition features a new structure which allows for faster, easier access to information. Thieme Flexibook Burmester G., Pezzutto A., Ulrichs T., Aicher A. Thieme Medical Publishers; 2003; pp.322; ISBN: 0865779643, 3131267410 A pocket atlas flexibook on this dynamic and wide-ranging field, indispensable for students of medicine and biology alike. Complex processes are well-illustrated in clear images that are not burdened with unnecessary details. Following an introductory part and a section on laboratory methods in immunology, the bulk of the book concentrates on the manifestations of immunological diseases in the human body, providing comprehensive capsule descriptions of all common immune diseases. Color Atlases of medicine and science Riede U., Werner M. Thieme Medical Publishers; 2004; pp.457; ISBN: 1588901173, 3131277815 Book description The pocket atlas is an excellent reference work that presents pathologic findings in all clinically relevant fields, using high-quality photographs and concise, well structured explanatory texts. Images include color photos and micrographs. Electron microscopic images are included where necessary. Clear schematic drawings illustrate procedures such as the course of infections, etc. Text boxes on clinical and morphological aspects, on complications, and with easy-to-remember mnemonic summaries are set off in color. |
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