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28.05.2015 18:29                   URL #101 Dear Colleagues, Please forward this research opportunity at the University of Texas Medical School in Houston, TX to any graduates looking for a postdoc position: A postdoctoral position funded by the NIH is available immediately in Dr. Yi-Ping Li's lab in the Dept. of Integrative Biology and Pharmacology, at the University of Texas Houston Medical School. Prospective candidates will join a research team to study the molecular mechanism of cancer cachexia, a wasting syndrome characterized by muscle wasting. This area of research has been identified by the National Institute of Cancer as one of the "provocative questions" with very high significance. Utilizing cell and molecular biological approaches, the team has made significant progress recently in uncovering the signaling mechanism of cancer cachexia using cell culture and animal models (PMC3199382, PMC3534568 and PMC3688742). More recently the team has been focusing on identifying tumor-generated factors that directly cause muscle wasting. Individuals with recent Ph.D. and strong background in cell biology, molecular biology and muscle physiology are encouraged to apply. Int! erested individuals should send CV and cover letter to Dr. Yi-Ping Li via email to yi-ping.li@uth.tmc.edu.

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02.06.2015 01:18                   URL #102 Postdoctoral Position in Stress Biology A postdoctoral scholar position is available in the laboratory of James Herman at the University of Cincinnati. The Herman laboratory focuses on stress neurobiology, using state-of-art methods to understand brain circuitry underlying stress regulation and stress pathology in rodent models. Funded projects address the role of corticolimbic circuitry in control of behavioral, endocrine and cardiovascular responses to stress. The Herman lab is part of a robust stress neurobiology group in the Department of Psychiatry and Behavioral Neuroscience, which includes investigators studying animal models of psychiatric disease (depression, PTSD and panic), interactions between stress and neurologic disease (epilepsy, Parkinson’s Disease) and the relationship between and cardiovascular pathologies. Successful candidates would be expected to have a PhD in Physiology, Neuroscience or a related discipline. For consideration, please submit a current CV, a statement of research interests and contact information for three referees to james.herman@uc.edu by August 1, 2015. The University of Cincinnati is an affirmative action/equal opportunity employer. UC is a smoke-free work environment. James P. Herman, PhD Donald C. Harrison Professor Department of Psychiatry and Behavioral Neuroscience Director, UC Neurobiology Research Center Director, Stress Neurobiology Laboratory University of Cincinnati 2170 East Galbraith Road Cincinnati, OH 45237-0506 Phone: 513-558-4813 Fax: 513-558-9104 website: https://webcentral.uc.edu/eprof/reports/vie...D%3D&wrapper=no

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04.06.2015 21:27                   URL #103 Postdoc Position in the Center for Craniofacial Research at the School of Dentistry, University of Texas at Houston A POSTDOC POSITION POSITION SUMMARY We are seeking a highly motivated postdoc to work on the role of transcription factors in craniofacial development and disorders. This position is available at the Center for Craniofacial Research at the School of Dentistry, University of Texas at Houston. Our lab has been working on a novel genetic interaction between TWIST1 and IRF6 transcription factors during craniofacial development. We propose to use this mouse model to identify genetic risk factors in patients affected with mandibular abnormalities and cleft palate as the case in Pierre Robin Sequence (PRS). Our goals are to understand the mechanism of the genetic interaction and to test the hypothesis that patients with PRS carry DNA variations in genes involved in the IRF6-TWIST1 regulatory pathway during embryonic development. The postdoc will be responsible to conduct research activities, support and lead lab projects, report and write manuscripts for publications, and also directly work with students in the lab under the direction of the PI. The postdoc will perform lab experiments and in vivo studies using mice as an animal model to study the role of transcription factors and signaling molecules in face and jaw development. We also use ex-vivo mandibular organ and human cell lines to perform biochemical and molecular assays to test biological hypotheses that will allow us to understand the mechanism of action of gene regulation and protein activities. This position is available for one year with the possibility of extension based upon the funding situation. A PhD degree in biochemistry, molecular biology, molecular genetics or other relevant basic sciences is required. Knowledge in human genetics is preferential but not necessary. A postdoc experience of 0-2 years is preferential. Please contact Dr. Walid Fakhouri, Walid.D.Fakhouri@uth.tmc.edu, at School of Dentistry for information and interest in the position.

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05.06.2015 00:11                   URL #104 We have a Postdoctoral Position available in Stress Neurobiology – University of South Carolina School of Medicine A post-doctoral position is available in the laboratory of Dr. Susan Wood at the Department of Pharmacology, Physiology and Neuroscience at the University of South Carolina School of Medicine. This VA funded position is part of a 4-year grant investigating the role of the immune system in stress-related pathology. The Wood lab’s research is focused on how the brain communicates with the periphery and how dysfunction in this communication following stress exposure can lead to pathology. This multidisciplinary project will use 1) molecular biological approaches combined with in vivo cardiac physiology to identify mechanisms mediating pathological responses to stress and 2) in vivo electrophysiology to determine neural mechanisms driving susceptibility and resiliency to stress. The selected candidate will become a member of the interdisciplinary collaborating team of investigators studying the neuro-immune mechanisms driving stress-induced dysfunction in synaptic plasticity (Lawrence Reagan, PI), cardiovascular function (Susan Wood), cholinergic signaling and cognition (Jim Fadel), immunotoxicology (Jennifery Nyland) and behavior (Marlene Wilson). The ideal candidate will be a recent Ph.D. graduate with experience in a related field (e.g., pharmacology, physiology, neuroscience or immunology) with experience using in vivo approaches (e.g., surgical techniques, behavioral analyses, tissue dissection, electrophysiology etc.). The individual must be highly motivated and able to work independently as well as part of a dynamic team. The demonstrated ability to publish research findings is critical. Excellent English speaking/writing skills required. Applications will be reviewed on a rolling basis and will be accepted until the position is filled. The position offers standard NIH salary levels, health insurance, as well as paid vacation and sick leave. Please email your CV, names and emails of 3 references, and a cover letter describing your fit for the position and scientific research interests/experience to Dr. Susan Wood (susan.wood@uscmed.sc.edu). Wood lab websites: http://ppn.med.sc.edu/swood.asp http://cobre.med.sc.edu/wood.asp Recent press: https://www.yahoo.com/health/ease-depressio...5226242722.html http://www.aspet.org/March_30_Finell/ Susan K. Wood, PhD Assistant Professor Department of Pharmacology, Physiology & Neuroscience Columbia, SC 29208 Office: 803-216-3522 Website: http://ppn.med.sc.edu/swood.asp

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08.06.2015 18:44                   URL #105 Postdoctoral Research Position (open immediately, June 2015) A position is available in the Dr. Margaret Conner’s laboratory in the Department of Molecular Virology and Microbiology at Baylor College of Medicine. The project’s primary goal is to define protective immunological pathways that are induced during Clostridium difficile infection (CDI) using a mouse model. The studies will focus on the role of IgA and gastrointestinal lymphoid tissues in protective immunity against CDI. The successful candidate must have experience working with mouse models, and preference will be given to those with prior experience in models of infectious diseases, immunologic studies, and/or flow cytometry. Applicants with other relevant expertise will be considered. Duties of the successful candidate will include but are not limited to, (1) independently design and perform experiments, (2) analyze data and write manuscripts for publication, (3) contribute to training and oversight of other lab personnel, (4) coordinate collaborations with other investigators at BCM, Texas Medical Center, and at other national/international institutions, (5) develop new ideas, approaches, and skills to apply to the project. Applicants should submit a curriculum vitae and the names and contact information of three references electronically to Dr. Margaret E. Conner (mconner@bcm.edu).

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10.06.2015 21:59                   URL #106 Job Description The University of Texas MD Anderson Cancer Center invites applications for a postdoctoral fellowship. This is a full­time, hands­on laboratory post­doctoral research position in the Department of Lymphoma/Myeloma. Applicants must have a recent Ph.D. and/or M.D. with focused research on the relevant subjects. The successful candidate will have a track record of productivity in research and have the talent and dedication to take advantage of the vast resources available at The University of Texas MD Anderson Cancer Center. We are looking for highly motivated and interactive colleagues, who are interested in applying his/her knowledge in in vivo tumor models, functional genomics, cancer biology, cell signaling, molecular biology, and pharmacology and to solve some therapeutic challenges in lymphoma, are highly encouraged to apply. Experience in one of the following areas is preferred: animal models, cancer biology, experimental therapeutics, pharmacology, and metabolisms, or molecular biology. The University of Texas MD Anderson is centered in the vibrant research environment of the Houston Texas Medical Center, which includes Baylor College of Medicine, The University of Texas Medical School, the Methodist Hospital Research Institute, and Rice University, and ranks 1st in the number of awarded grants from National Cancer Institute. It offers active graduate and postdoctoral training programs and the unmatched scientific environment of the Texas Medical Center, the world’s largest biomedical center. Interested candidates should send a CV with 3 references and a brief description of recent research interests, activities, and career goals. M. D. Anderson Cancer Center is an equal opportunity employer and does not discriminate on basis of race, color, national origin, gender, sexual orientation, age, religion, disability or veteran status except where such distinction is required by law. All positions at The University of Texas M. D. Anderson Cancer Center are security sensitive and subject to examination of criminal history record information. Smoke­free and drug­free environment. Contact: Laura Lam Lymphoma/Myeloma The University of Texas M. D. Anderson Cancer Center 1515 Holcombe Blvd. Houston, TX 77030 United States Email: LTLam@mdanderson.org Institution Web Site: http://www.mdanderson.org

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16.06.2015 20:14                   URL #107 Postdoctoral position at The Ohio State University, Columbus Ohio in the laboratory of Dr. Susan Travers. NIH-funding is available for 4 years to investigate novel mechanisms for detecting amino acids, complex carbohydrates and simple sugars utilizing in vivo neurophysiology and T1R receptor knockout mice. There is also an opportunity to contribute to ongoing experiments of inhibitory processing in the gustatory system using optogenetics in combination with in vivo and vitro neurophysiological and behavioral experiments. Salary is commensurate with NIH guidelines. The successful candidate will have a PhD or other doctoral degree in neuroscience or a related field. Experience in neurophysiology is desirable but not essential. Interested candidates should forward any questions, along with a CV and contact information for three references to Susan Travers, PhD, travers.3@osu.edu Susan Travers Professor, Biosciences Division of Biosciences, College of Dentistry The Ohio State University 305 West 12th Avenue Columbus, Ohio 43210 travers.3@osu.edu (614)361-0800 (cell) (614)292-6366 (work)

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22.06.2015 19:36                   URL #108 An NIH-funded postdoctoral position is available in the laboratory of Dr. Patrick Mueller in the Department of Physiology at Wayne State University School of Medicine (http://physiology.med.wayne.edu/). Along with several other faculty at Wayne State, Dr. Mueller's research focuses on neural control of circulation with emphasis on sympathetic control of blood pressure. Current interests in the laboratory include physical activity/inactivity, hypertension, and neural plasticity. Applicants are expected to have a Ph.D., M.D., or comparable doctoral degree at the time of the appointment. Experience in cardiovascular physiology, especially in neural control of the circulation is highly desirable. The ideal candidate will have a good record of publications and excellent communication and laboratory skills. Preference will be given to candidates with experience in any one or more of the following techniques: sympathetic nerve recordings; electrophysiology; immunohistochemistry, western blotting, laser capture microdissection, rtPCR, neuronal reconstruction, and magnetic resonance imaging. Salary will be commensurate with experience according to NIH guidelines for postdoctoral stipend levels. The fellow will receive comprehensive fringe benefits including medical, dental, vision, and life insurance. This position is eligible for funding in part by the Office for the Vice President for Research if the candidate is a U.S. citizen or permanent resident. Please send a curriculum vitae, anticipated start date and the names of three references via email (pmueller@med.wayne.edu) to Patrick J. Mueller, Ph.D; Associate Professor of Physiology; Wayne State University School of Medicine. Applications will be accepted until a candidate is selected. Wayne State University is an equal opportunity employer.

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29.06.2015 21:21                   URL #109 Postdoctoral position available in Respiratory Physiology and the Control of Breathing An NIH-funded postdoctoral position is available in the laboratory of Dr. Matthew Hodges in the Department of Physiology at The Medical College of Wisconsin (http://www.phys.mcw.edu/) located in Milwaukee, Wisconsin. Dr. Hodges' research focuses on neural control of breathing with emphasis on mechanisms of ventilatory chemoreflexes. Current interests in the laboratory include the molecular mechanisms of central CO2/pH chemoreception, contributions of pH-sensitive potassium channels to ventilatory control and the role(s) of brainstem serotoninergic neurons in physiological control systems. Applicants are expected to have a Ph.D., M.D., or comparable doctoral degree at the time of the appointment. Experience in respiratory physiology, especially in neural control of the breathing is highly desirable. The ideal candidate will have a good record of publications and excellent communication and laboratory skills. Preference will be given to candidates with experience with one or more of the following techniques: PCR, RNA extraction, cDNA library preparation, RNA Sequencing and/or bioinformatics, with preference to those highly skilled in electrophysiologic (patch clamp) techniques. Salary will be commensurate with experience according to NIH guidelines for postdoctoral stipend levels. Please send a curriculum vitae, representative publication(s), anticipated start date and the names of three references via email (mhodges@mcw.edu) to Matthew R. Hodges, Ph.D; Assistant Professor of Physiology, Medical College of Wisconsin. Applications will be accepted until a candidate is selected. The Medical College of Wisconsin is an equal opportunity employer. Matthew R. Hodges, PhD Assistant Professor Department of Physiology Neuroscience Research Center Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee, WI 53226

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01.07.2015 17:26                   URL #110 Postdoctoral Position in Neural Control of Cardio-Respiratory Function A Postdoctoral Research Associate position is available immediately in the Department of Cellular and Integrative Physiology at the University of Nebraska Medical Center to participate in cardiovascular/respiratory research, which includes the function and electrophysiology of autonomic neurons. The position will be supervised by Professor Harold Schultz, Ph.D. Training emphasis is placed on the study of chemoreflexes, cardio-pulmonary reflexes and central nervous control of sympathetic/parasympathetic nerve activity, ventilation, cardiac and renal function in disease states such as heart failure, hypertension, and diabetes. Neuro-vascular and sympatho-respiratory coupling are two potential areas of interest. The successful applicant will be expected to master modern cellular, molecular, electrophysiological and integrative approaches to address questions related this area of research in conscious animals models of cardiovascular disease. Previous experience in neural control of the cardiovascular/respiratory system, one or more of the research approaches described herein, and care and use of chronic animals models is preferred but not required; however, the successful applicant will be expected to learn and apply these skills. Applications must be submitted online at http://unmc.peopleadmin.com/postings/23088 For additional information on the position, please contact: Harold D. Schultz, Ph.D. Department of Cellular and Integrative Physiology University of Nebraska Medical Center 985850 Nebraska Medical Center Omaha, NE 68198-5850 Email: hschultz@unmc.edu Phone: 402-559-7167

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01.07.2015 17:27                   URL #111 Host Pathogen Interactions in Cystic Fibrosis A postdoctoral fellowship is available to investigate host-pathogen interactions in lung epithelial cells. Projects focus on how airway pathogens (i.e., Pseudomonas aeruginosa, and viruses, etc.) interact with the host (polarized human airway epithelial cells) to cause lung damage and disease. This position involves collaboration with microbiologists and cell biologists, and also involves translational research utilizing clinical samples from patients with CF. For references see: Stanton, B.A., et al, Pseudomonas aeruginosa reduces VX-809 stimulated F508del-CFTR chloride secretion by airway epithelial cells. PLoS One, May 27;10(5), 2015., and Bomberger, J.M., et al, Pseudomonas aeruginosa Cif protein enhances the ubiquitination and proteasomal degradation of the transporter associated with antigen processing (TAP) and reduces major histocompatibility complex (MHC) class I antigen presentation. J. Biol. Chem. 289(1):152-62, 2014. Experience in microbiology, cell biology, and molecular biology is required, and experience in live cell imaging, and confocal microscopy is desirable. Email a curriculum vitae, letter of research experience and interests, and names of three references to: Bruce A. Stanton, Ph.D., Director of the Lung Biology Center at Dartmouth, at bas@Dartmouth.edu. Dartmouth is an equal opportunity/affirmative action employer and strongly encourages applications from women and minority candidates. Bruce A. Stanton, Ph.D. Andrew C. Vail Professor Professor of Microbiology and Immunology Director, Dartmouth Lung Biology Center Director, Dartmouth Center for the Environmental Health Sciences 615 Remsen Building The Geisel School of Medicine at Dartmouth Hanover, NH 03755 603-650-1775 Bruce.A.Stanton@Dartmouth.edu

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02.07.2015 18:57                   URL #112 Postdoctoral Fellow Position in Cardiovascular Physiology at Georgia Regents University, Department of Physiology. A postdoctoral position is available in the laboratory of Dr. Eric Belin de Chantemele at Georgia Regents University to study the sex-specificity of the mechanisms controlling blood pressure in the context of obesity, and the role of the adipokine leptin in the control of autonomic and vascular functions. The postdoctoral fellow's responsibilities will include: measuring blood pressure via radio-telemetry, conducting physiological and molecular biological experiments using dissected vessels from mouse and cells freshly isolated from tissues, analyzing research data using different computer softwares, generation of preliminary data for grant applications, writing grants and manuscripts, coordinating with other investigators for lab research. Successful candidate must have a Ph.D. in the biomedical sciences, M.D. or equivalent degree. A strong record of productivity in cardiovascular physiology is required. Interested applicants should send a C.V., a letter of interest, to ebelindechanteme@gru.edu. Eric J. BELIN de CHANTEMELE, D.Sc., FAHA Assistant Professor, Physiology Department, CA3147 Medical College of Georgia, at Georgia Regents University 1120 15th Street, Augusta, GA 30912 Tel: 706 721 7805 Fax: 706 721 7299 Email: ebelindechanteme@gru.edu

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04.07.2015 19:21                   URL #113 Postdoctoral position in Biochemistry: Temple University, Philadelphia, PA An NIH-funded postdoctoral fellow position is available in translational research for ambitious and productive applicants in the laboratory of Dr. Beata Kosmider at Temple University. The goal of the study is to explore the mechanisms involved in lung injury induced by environmental factors and in human and murine emphysema with a focus on the impairment of the antioxidant defense system. Requirements: Recent Ph.D. or similar degree and strong background in biochemistry and molecular biology. Successful candidates must have extensive experience in molecular cloning, protein expression, and purification. Candidates with a background in X-ray crystallography and NMR are encouraged to apply. The successful candidate will develop and execute experimental procedures, interpret experiments, present results at scientific conferences and prepare manuscripts for publication. The candidate will have the ability to work both independently and as part of a team. To apply, please email your CV and a cover letter summarizing your previous research experience along with the contact information of three references to: beata.kosmider@temple.edu.

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04.07.2015 19:23                   URL #114 Postdoctoral Position in Vascular Biology: Johns Hopkins University A postdoctoral research position in vascular biology is available immediately in the laboratory of Nick Flavahan at Johns Hopkins University, Baltimore, Maryland. The laboratory embraces a multidisciplinary approach to vascular research, with major projects focused on molecular and physiological mechanisms regulating postnatal maturation of arterial structure and function, and the mechanisms contributing to the development of vascular disease. The ideal candidate will have a solid background in vascular biology with prior experience in studying the molecular and/or physiological regulation of the vascular system. Candidates must have (or expect to receive) a PhD, MD or MD/PhD degree, have prior publications and be hard-working and motivated to pursue innovative scientific research. Competitive salary and an exceptional research environment are available at Johns Hopkins University. Please send a CV, a letter of interest, and the names and contact information of three references to: nflavah1@jhmi.edu. Nick Flavahan PhD Edward D. Miller Professor, Director of Research, Vice Chair, Department of Anesthesiology and Critical Care Medicine, Johns Hopkins University.

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07.07.2015 17:06                   URL #115 NEW POSTDOC POSITION A postdoctoral position is available in our internationally known research group, which is focused toward understanding the molecular, cellular and physiological principles of nuclear receptor signaling in normal target cells and endocrine cancers. Successful applicants will utilize state-of-the-art technologies (i.e. established mouse models, lentiviral-mediated gene transfer, microarray, and proteomics) to address important questions concerning nuclear receptor and coregulator function in normal physiological processes and disease states, such as breast and endometrial cancer. Applicants with a strong background in molecular biology and in using animal systems are encouraged to apply. Salaries will be the upper competitive end of the national norm. Applicants should have received their Ph.D. and or M.D. within the past one to two years and, if necessary, be eligible for an appropriate U.S. visa. Current curriculum vitae, a brief statement describing prior research and future goals, and three letters of recommendation (all required before interview) should be sent to: Dr. John P. Lydon, Department of Molecular & Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030-3498; Fax: 713-790-1275 or email: jlydon@bcm.tmc.edu. John P. Lydon, Ph.D., Associate Professor, Department of Molecular & Cellular Biology, Room #M732A, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, 77030, USA

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09.07.2015 18:17                   URL #116 Seeking highly motivated scientist for a postdoctoral position in the laboratory of Dr. Sheng Wu at Division of Endocrinology/Metabolism, Department of Pediatrics, Johns Hopkins University School of Medicine. We are interested in the pathophysiology of obesity and hyperandrogenemia, particularly in reproductive and metabolic dysfunction. In vivo and in vitro techniques are used in the investigations. Applicants should have a PhD degree and send their CV, a cover letter stating their research interests, and contact information for three references to: Sheng Wu, PhD, swu24@jhmi.edu. Johns Hopkins University is an equal opportunity employer. Salary will be commensurate with level of experience.

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10.07.2015 17:37                   URL #117 Postdoctoral Position in Neural Control of Cardiovascular Function and Stroke A Postdoctoral Fellow position is immediately available in the laboratory of Professor Glenn Toney, Ph.D. in the Department of Physiology at the University of Texas Health Science Center at San Antonio. Preference will be given to applicant with expertise in the use of modern electrophysiological and live cell imaging methodologies. The successful applicant will be expected to master the implementation of viral vector technologies to manipulate neuronal gene/protein expression. Studies will investigate neural adaptations to chronic intermittent hypoxia (modeling sleep apnea), focusing on pre-autonomic neurons of the hypothalamic paraventricular nucleus (PVN). Training goals are to explore mechanisms underlying activation and participation of PVN neurons in arterial hypertension as well as their vulnerability to focal ischemic stroke. Previous experience in neural control of cardio-respiratory function is preferred, but not required. For additional information, please contact: Prof. Glenn M. Toney, Ph.D., F.A.H.A Department of Physiology – MC7756 University of Texas Health Science Center 7703 Floyd Curl Drive San Antonio, TX 78229-3900 Email: toney@uthscsa.edu Phone: 210-567-4372

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11.07.2015 20:34                   URL #118 A Postdoctoral Fellow position is available immediately in the laboratory of Colleen M Novak in the Department of Biological Sciences and School of Biomedical Sciences at Kent State University. The postdoctoral researcher will work on a collaborative project using viral vectors and related methods to investigate hypothalamic modulation of peripheral metabolism through autonomic control. Preference will be given to applicants with expertise in stereotaxic surgery. To apply, please create an account and apply to: https://jobs.kent.edu/ Also send CV and letters of reference to cnovak13@kent.edu ------------------------------ Colleen Novak Ph.D. Associate Professor Kent State University Kent, OH (330) 672-2306 ------------------------------

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11.07.2015 20:36                   URL #119 TRAINING OPPORTUNITY: PhD STUDENT AND POST- DOCTORAL FELLOW in CANADA TITLE OF STUDY: Impact of exercise on brain and cognitive health in older adults. INVESTIGATORS: University of Calgary (Dr Marc J Poulin, Dr Christine Friedenreich, Dr Michael D Hill, Dr David B Hogan, Dr Stewart Longman) and Dalhousie University (Dr Gail Eskes). We are looking for a doctoral student and a postdoctoral fellow in human vascular or cognitive neurosciences who are interested in completing a studentship/fellowship as part of a grant-funded project investigating the effects of exercise on cerebrovascular function and cognition in older adults. These positions will be based in the Laboratory of Human Cerebrovascular Physiology (PI is Professor Marc Poulin) at the University of Calgary. Research activities will take place within the Cumming School of Medicine at the University of Calgary. Responsibilities will include being part of an interdisciplinary research project that is enrolling healthy human volunteers aged 55-75 years old, measurement of several physiologic, sleep, genetic cognitive and other factors and completion of an exercise intervention. The successful candidates will be involved with laboratory-based experiments, helping coordinate the exercise training intervention, and in presentations of the research at local and international scientific meetings and preparation of manuscripts that emerge from this research. Candidates should have some or all of the following attributes: i) a strong background in integrative human physiology or psychology, ii) good communication skills (written/spoken English), iii) an excellent academic record, iv) a keen desire to learn, and v) previous research experience working with human volunteers and/or patients in a physiology or psychology research environment. Prior experience with ultrasound imaging, exercise training programs, biochemistry laboratory techniques (e.g., blood sampling, centrifugation, storage, and assay analyses) and/or cognitive aging or neuropsychology will be major assets. However, additional training will be provided to ensure that the successful applicants have the skills required to meet the objectives of the project. More information about our research is located on our website: http://www.ucalgary.ca/poulin Sample publication leading up to this project: Tyndall AV et al. The Brain-in-Motion study: effect of a 6-month aerobic exercise intervention on cerebrovascular regulation & cognitive function in older adults. BMC Geriatrics 2013. PMID: 23448504. Davenport MH et al. Cerebrovascular reserve: an important between fitness and cognitive function. Exercise and Sport Sciences Reviews PMID: 22504726. Eskes GA et al. Contribution of physical fitness, cerebrovascular reserve and cognitive stimulation to cognitive function in postmenopausal women. Frontiers in Aging Neuroscience PMID: 21048898. Pialoux V et al. Effect of cardiorespiratory fitness on vascular regulation and oxidative stress in postmenopausal women. Hypertension PMID: 19786647. Brown AD et al. Effects of Cardiorespiratory Fitness and Cerebral Blood Flow on Cognitive Outcomes in Older Women. Neurobiology of Aging PMID: 19111937. Candidates should submit a letter of intent outlining their qualifications and career objectives, an unofficial transcript of academic record, complete list of publications and awards, along with names of 3 referees who have agreed to be contacted. Applications will be accepted until the position is filled. Funding is secured for 2-years with the possibility of extension for an additional 3 years. Salary will be commensurate with University of Calgary policies. Send your complete application package to: Professor Marc Poulin, PhD DPhil Department of Physiology & Pharmacology, University of Calgary HMRB-210, 3330 Hospital Drive NW Calgary, Alberta, T2N 4N1, CANADA or by email to: poulin@ucalgary.ca ------------------------------ Marc Poulin Ph.D., D.Phil. Professor Calgary AB (403) 210-8420

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13.07.2015 23:06                   URL #120 Dr. Peter Zage's lab at Texas Children's Hospital/Baylor College of Medicine is seeking a post doctoral fellow for work in developmental therapeutics for pediatric solid tumors, primarily neuroblastoma. Our laboratory goals are to develop novel treatments and identify novel targets for therapies for childhood cancer, focusing primarily on children with neuroblastoma, a childhood malignancy with poor prognosis. Primary project areas include studies of the efficacy and mechanisms of action of novel therapeutic agents and combinations in preclinical neuroblastoma model systems and also investigations of the pathways involved in the regulation of growth factor receptor trafficking in order to understand their role in responses to treatment. A post-doctoral fellow will be expected to contribute to the design and conduct of research projects within these areas of active research through the independent design, conduct, and analysis of experiments and their results; preparation, presentation, and publication of results under the direction of the principal investigator (PI); and submission of applications for post-doctoral fellowships with guidance and assistance from the PI. In addition, a post-doctoral fellow will be expected to teach techniques to other laboratory trainees and members, to train and oversee other lab members as determined by the PI, and to contribute to general laboratory maintenance, including equipment maintenance and ordering of supplies as needed. The ideal candidate will bring new expertise to enhance and expand the research program, and will be experienced in molecular and cellular biological techniques, including DNA and RNA manipulations (e.g. PCR, RNA interference, etc.), protein biochemistry (e.g. electrophoresis, Western blot, etc.) in vitro studies in human cell lines, and tumor tissue assays. Experience/interest in working with animals is preferred but not required. For more information or to apply for this position, please contact: Peter Zage, MD PhD zage@bcm.edu pezage@txch.org phone: 832-824-4615 http://txch.org/doctors/dr-peter-zage/

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14.07.2015 22:23                   URL #121 Postdoctoral Fellow, Cedars-Sinai Medical Center Heart Institute Under the guidance of the Director of Molecular Cardiobiology (Dr. Roberta A. Gottlieb) at the Cedars-Sinai Heart Institute, the candidate will focus on a grant-funded project to study the impact metabolic syndrome has on cardiac autophagy and ischemia/reperfusion injury. Candidate must be creative, self-motivated and a team player. A doctorate (Ph.D., M.D., or D.V.M.) in an area broadly related to the areas of metabolism, and cardiac research is required. Successful candidate must have demonstrated an aptitude to plan and execute experimental protocols and procedures related to biochemistry and molecular/cell biology. Must be willing to conduct animal research and have experience in working with rodent models. Experience with mouse Langendorff or working heart preparations is desirable, as is expertise in CRISPR/Cas9 technology. Candidates should submit a letter of intent to Ezequiel.Noyola@cshs.org outlining their qualifications and career objectives, an unofficial transcript of academic record, complete list of publications and awards, along with names of 3 referees who have agreed to be contacted. Applications will be accepted until the position is filled. Funding is secured for 3 years. Salary will be commensurate with Cedars-Sinai policies. A description of ongoing research in the Gottlieb Lab is here: http://www.cedars-sinai.edu/Research/Resea...-Lab/index.aspx Pertinent Publications: 1. Gottlieb RA, Andres AM, Sin J, Taylor DP. Untangling autophagy measurements: all fluxed up. Circ Res. 2015 Jan; 116(3):504-14. doi:10.1161/CIRCRESAHA.116.303787. PMID: 25634973; PMCID: PMC4313387. 2. Linton PJ, Gurney M, Sengstock D, Mentzer RM Jr, Gottlieb RA. This old heart: Cardiac aging and autophagy. J Mol Cell Cardiol. 2015 Jun; 83:44-54. doi:10.1016/j.yjmcc.2014.12.017. PMID: 25543002; PMCID: PMC4459942. 3. Andres AM, Stotland A, Queliconi BB, Gottlieb RA. A time to reap, a time to sow: mitophagy and biogenesis in cardiac pathophysiology. J Mol Cell Cardiol. 2015 Jan; 78:62-72. doi: 10.1016/j.yjmcc.2014.10.003. PMID: 25444712; PMCID: PMC4268279. 4. Trudeau KM, Gottlieb RA, Shirihai OS. Measurement of mitochondrial turnover and life cycle using MitoTimer. Methods Enzymol. 2014; 547:21-38. doi:10.1016/B978-0-12-801415-8.00002-3. PMID: 25416350. 5. Ferree AW, Trudeau K, Zik E, Benador IY, Twig G, Gottlieb RA, Shirihai OS. MitoTimer probe reveals the impact of autophagy, fusion, and motility on subcellular distribution of young and old mitochondrial protein and on relative mitochondrial protein age. Autophagy. 2013 Nov; 9(11):1887-96. doi: 10.4161/auto.26503. PMID: 24149000; PMCID: PMC4028338. 6. Hernandez G, Thornton C, Stotland A, Lui D, Sin J, Ramil J, Magee N, Andres A, Quarato G, Carreira RS, Sayen MR, Wolkowicz R, Gottlieb RA. MitoTimer: a novel tool for monitoring mitochondrial turnover. Autophagy. 2013 Nov; 9(11):1852-61. doi: 10.4161/auto.26501. PMID: 24128932; PMCID: PMC4028337. 7. Andres AM, Hernandez G, Lee P, Huang C, Ratliff EP, Sin J, Thornton CA, Damasco MV, Gottlieb RA. Mitophagy is required for acute cardioprotection by simvastatin. Antioxid Redox Signal. 2014 Nov; 21(14):1960-73. doi:10.1089/ars.2013.5416. PMID: 23901824; PMCID: PMC4208607. 8. Jahania SM, Sengstock D, Vaitkevicius P, Andres A, Ito BR, Gottlieb RA, Mentzer RM Jr. Activation of the homeostatic intracellular repair response during cardiac surgery. J Am Coll Surg. 2013 Apr; 216(4):719-26; discussion 726-9. doi:10.1016/j.jamcollsurg.2012.12.034. PMID: 23415552; PMCID: PMC3724756. 9. Huang C, Andres AM, Ratliff EP, Hernandez G, Lee P, Gottlieb RA. Preconditioning involves selective mitophagy mediated by Parkin and p62/SQSTM1. PLoS One. 2011; 6(6):e20975. doi: 10.1371/journal.pone.0020975. PMID: 21687634; PMCID: PMC3110820. Roberta A. Gottlieb, M.D. Professor of Medicine Director of Molecular Cardiobiology Dorothy and E. Phillip Lyon Chair in Molecular Cardiology Cedars-Sinai Heart Institute Barbra Streisand Women's Heart Center 127 S. San Vicente Blvd. AHSP9105 Los Angeles, CA 90048 (424) 315-2556

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15.07.2015 18:19                   URL #122 USAISR OCULAR TRAUMA POSTDOCTORAL OPPORTUNITY #1 The Ocular Trauma Task Area at the United States Army Institute of Surgical Research (USAISR) is seeking a candidate for a postdoctoral position. The objective of our research program is to develop and evaluate treatments for ocular trauma. The research focus area for this position is to elucidate mechanisms of blast-induced ocular injury and their effects on pain and inflammatory signaling pathways. Research projects include: 1.Animal models of blast-induced ocular injury 2.Analysis of neuropeptide profiles in sensory tissues exposed to blast overpressure 3.Investigation of pharmacological antagonists in blast-induced ocular pain and inflammation. Qualified candidates must be highly motivated, independent individuals with a PhD in physiology, cell biology, biochemistry, or a related field. Candidates must have exceptional laboratory and written communication skills andthe ability to work both independently and cooperatively within a team. Experience with large and small animals, primary tissue culture, histology, molecular and biological techniques is essential. Individuals with experience in neuronal primary cell culture, confocal microscopy, animal behavior and animal handling are highly encouraged to apply. The stipend/salary is $48,000 and up depending on prior experience. The successful candidates will be joining a research program that focuses on understanding potential mechanisms involved in battlefield ocular trauma, and developing new treatment modalities to improve vision and sensory restoration. Emphasis is placed on transitioning products from pre-clinical to clinical testing in a collaborative environment involving researchers and clinicians. The USAISR is co-located with San Antonio Military Medical Center (SAMMC) in San Antonio, TX, which enables the research organization to have a unique in-depth understanding of combat injuries, civilian trauma and the clinical challenges faced by the physicians and surgeons who treat them. This creates a unique environment for translational research. To apply, applicants must submit their curriculum vitae, brief description of research interests and career goals, and email contact information for three references. Applicants with US citizenship are preferred. More information at: http://www.usaisr.amedd.army.mil/training_...p_OCULAR_1.html Or contact, Gina L. Griffith, PhD, gina.l.griffith8.mil@mail.mil

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16.07.2015 18:37                   URL #123 Postdoctoral positions in Hearing and Communication Neuroscience at USC Hearing & Communication Neuroscience (HCN) is an inter-disciplinary training program for graduate students, post-doctoral scholars, and physician-scientists at the University of Southern California. Cutting-edge research labs are investigating mechanisms of audition and vocal communication, and are located in the Departments of Otolaryngology, Regenerative Medicine, Physiology & Biophysics, Neurobiology, Linguistics, Psychology, and Biomedical Engineering. Our training program brings together researchers spanning multiple disciplines, ranging from genetics and cell-molecular biology to cognitive, systems, and behavioral neuroscience. HCN labs are investigating mechanisms underlying audition and vocal communication at the level of individual molecules and cells, neural circuits, and cognitive constructs such as neural representations of memories, plans and actions. Our program is supported by an NIH training grant from the National Institute of Deafness & Communication Disorders, and currently has openings for post-doctoral fellows. To initiate an application please contact individual HCN Faculty listed on our website at http://dornsife.usc.edu/hcn/ ------------------------------ Sarah Bottjer Ph.D. Professor Los Angeles CA (213) 740-9183 ------------------------------

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20.07.2015 01:53                   URL #124 A postdoctoral position is available immediately in the laboratory of Dr. JoAnne Richards, Department of Molecular and Cellular Biology at Baylor College of Medicine. Research in the Richards’ lab focuses on the hormonal control of ovarian biology at the molecular and cellular levels. Specific mouse models are used to study factors that control ovarian follicular development, ovulation and ovarian cancer. In particular, the lab is analyzing: 1) the mechanisms of vascular remodeling that occur during ovulation; 2) p53, steroids and immune factors that impact ovarian cancer development and metastasis; and 3) FOXO1and FOXO3 regulation of normal follicle development and granulosa cell tumor formation. The research is funded by NIH and NCI grants. Salary will be commensurate with years of experience. Please contact JoAnne S. Richards, PhD at joanner@bcm.edu for additional information.

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01.08.2015 19:27                   URL #125 Postdoctoral Associate: Cardiac Signal Transduction and Cellular Biology Laboratory The postdoctoral associate will be a member of this laboratory led by Dr. Kapiloff and participate in current research which asks how the formation of multimolecular protein complexes confers specificity in intracellular cardiac myocyte signaling. A major focus of the lab has been the mAKAP scaffold protein that coordinates crosstalk between cAMP, calcium and MAP-kinase signaling pathways and that is important for the induction of myocyte hypertrophy and cardiac remodeling (http://pediatrics.med.miami.edu/childrens-heart-center/research/cardiac-signal-transduction-and-cellular/). A wide range of techniques are being used to address these questions including the biochemical analysis of recombinant proteins in vitro, culture of primary cardiac myocytes, live cell imaging using novel FRET sensors and the analysis of genetically-modified mouse models. Postdoctoral Associate: Neuronal Intracellular Signaling The postdoctoral associate will be a member of the signal transduction and cellular biology laboratory led by Dr. Kapiloff, Professor of Pediatrics and Medicine, and participate in current research which asks how the formation of multimolecular protein complexes confers specificity in neuronal intracellular signaling, particularly in relation to neuronal survival and neurite outgrowth. Qualified candidates must possess PhD degree. Experience in neuronal cell biology, molecular biology, cell biology and biochemistry, including live cell fluorescent microscopy is preferable. Computer proficiency and database knowledge, strong analytical, organizational and communication skills are required. An appropriate combination of education, certifications, and/or relevant work experience will be considered. Michael S. Kapiloff, M.D., Ph.D. Professor of Cardiology, Departments of Pediatrics and Medicine Director, Cardiac Signal Transduction and Cellular Biology Laboratory Interdisciplinary Stem Cell Institute University of Miami Miller School of Medicine Phone: 305-243-7863 (office) 305-243-7864 (lab) Regular Mail: R198 P.O. Box 016960 Miami, FL 33101 Сообщение было отредактировано Libra - 01.08.2015 19:28

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01.08.2015 19:29                   URL #126 Under the guidance of the Director of the Barbra Streisand Women's Heart Center (Dr. C. Noel Bairey Merz) at the Cedars-Sinai Heart Institute, the candidate will focus on a funded project to study the relationship between coronary microvascular dysfunction and left ventricular diastolic dysfunction in women with ischemic heart disease. Candidates should have the following attributes: 1) a strong background in integrative (human) physiology, 2) good communication skills (written/spoken English), 3) an excellent academic track record, 4) previous research experience working with human volunteers and/or patients, and 5) be creative, self-motivated and a team player. A doctorate (Ph.D., M.D.) in an area broadly related to the areas of integrative physiology, and cardiac research is required. Background in cardiac imaging preferred. Candidates should submit a letter of intent to debra.krems@cshs.org outlining their qualifications and career objectives, curriculum vitae, along with names of 3 referees who have agreed to be contacted. Applications will be accepted until the position is filled. Funding is secured for 3 years. Salary will be commensurate with Cedars-Sinai policies.

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01.08.2015 19:30                   URL #127 An NIH-funded Postdoctoral Fellow position is immediately available in the laboratory of Dr. Matthew R. Hodges at the Medical College of Wisconsin to study the contributions of specific ion channels and neurochemicals to the neural networks controlling breathing. Projects include studying the molecular mechanisms underlying cellular CO2 and pH sensing, contributions of pH sensitive ion channels to ventilatory chemoreflexes in vivo, and the role of excitatory neuromodulation in key sites of central chemoreception. Qualifications: Expertise with in vitro electrophysiology and molecular biology preferred. Required qualifications include a PhD or MD in Neuroscience or a related field. Send curriculum vitae and names and addresses of 3 references to Dr. Matthew R. Hodges, Assistant Professor in the Department of Physiology and Neuroscience Research Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA, or email to mhodges@mcw.edu. Applications will be reviewed in the order received, and the position filled when a suitable candidate is found. More information about the laboratory is available at http://www.phys.mcw.edu/fac_hodges.htm. Salary will be commensurate with relevant experience and based on established guidelines for postdoctoral fellows set by the NIH, and includes an excellent benefits package. Milwaukee is located in southeastern Wisconsin, about 90 minutes from Chicago, IL and Madison, WI. Milwaukee is on the shores of Lake Michigan, is host to the world's largest music festival (Summerfest), and has an old world charm, diverse cultures, historic neighborhoods, and is a great place to raise a family. The Medical College of Wisconsin is an Equal Opportunity employer. Best, Matthew R. Hodges, PhD Assistant Professor Department of Physiology Neuroscience Research Center Medical College of Wisconsin 8701 Watertown Plank Road Milwaukee, WI 53226

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10.08.2015 21:38                   URL #128 Postdoctoral fellow in Stem Cell and Cancer Biology Employer: Baylor College of Medicine Job Number: 4016510 Date Posted: 08/06/2015 Application Deadline: Open Until Filled Job Description We are seeking a highly motivated postdoctoral fellow to investigate the mechanisms that regulate hematopoietic stem cells and how leukemia cells arise from stem and progenitor cells. The lab (PI: D Nakada) is located in the Department of Molecular and Human Genetics of the Baylor College of Medicine. We study cell intrinsic and extrinsic mechanisms that regulate hematopoietic stem cell maintenance. We are interested in how epigenetic landmark demarcate different stem and progenitor population, and how epigenetic regulators control this distinction. We are also interested in how extracellular cues such as hormones (Nature, 505:555) and the microenvironment regulate hematopoietic stem cells. We are also funded to study the metabolic regulation of leukemia-initiating cells. We are particularly interested in how metabolic regulators allow leukemia-initiating cells to survive in the metabolically adverse conditions, and how diet affects their maintenance. We also have a funded program to study a novel epigenetic regulator in the pathogenesis of myelodysplastic syndromes. Candidates must have a Ph.D. and/or M.D. or equivalent degree and have excellent training in cell biology and molecular biology. A strong training background in stem cell biology and/or cancer biology is highly desirable. Candidates who wish to step in stem cell biology with strong bioinformatics or systems biology background is also encouraged to apply. To apply, please provide a CV, a summary of the previous research experience, future research interest and career goals, together with the contact information of three references to dnakadalab@gmail.com. Per the new policy of Baylor College of Medicine, applicants with their doctoral degree obtained in non-English countries and had no post-doctoral experience in the US/Canada/UK institutes must demonstrate their English language fluency by obtaining a score no less than 100 in TOEFL or 6.0 in IELTS within the past two years. Baylor College of Medicine is an Equal Access/Equal Opportunity/Affirmative Action Employer. Contact: Baylor College of Medicine Houston, TX United States Email: dnakadalabgmail.com Postdoctoral fellow in Stem Cell and Cancer Biology

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13.08.2015 17:57                   URL #129 An opening is available for a postdoctoral research fellow on an NIH Training Grant in the laboratory of I. David Weiner, M.D. in the Division of Nephrology, Hypertension and Renal Transplantation at the University of Florida. A wide variety of projects in this laboratory are ongoing and addressing novel aspects of the molecular regulation of renal ammonia metabolism and ammonia transport. Projects can be adjusted to the specific background and training desires of a successful applicant. Previous expertise in either renal physiology or ion transport is highly beneficial. Applicants must be eligible for funding through the NIH Training Grant mechanism. To be considered for this position, please send, as PDF files, a cover letter, statement of academic interest, CV and names of three references familiar with the applicant’s scientific background to I. David Weiner, M.D. at David.Weiner@medicine.ufl.edu. ------------------------------ I. David Weiner M.D. Prof of Medicine and Physiology and Functional Genomics University of Florida College of Medicine Gainesville, FL ------------------------------

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13.08.2015 21:59                   URL #130 The Engin laboratory is seeking a postdoctoral researcher to investigate the role of endoplasmic reticulum stress in type 1 diabetes by utilizing cellular, biochemical approaches and recently generated genetic mouse models. Highly motivated, hardworking candidates with a recent PhD in molecular biology, immunology, genetics or relevant fields are encouraged to apply. Experience and expertise in primary cell culture, flow cytometry/sorting, beta cell biology and animal studies is highly desired. Interested candidates should submit a letter of interest, curriculum vitae, and contact information for at least three references to Dr. Feyza Engin (fengin@wisc.edu) with a subject line states “Postdoc Application”. Feyza Engin, Ph.D. Assistant Professor Department of Biomolecular Chemistry, Department of Medicine, Division of Endocrinology, Diabetes and Metabolism University of Wisconsin-Madison School of Medicine and Public Health HF DeLuca Biochemical Sciences Building Room 6260B 440 Henry Mall Madison, WI 53706 Office Phone: 608-262-8667 Lab Phone: 608-262-6206 Fax: 608-262-5253

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22.08.2015 00:31                   URL #131 Systems Neuroscience Postdoctoral position: Neurophysiology of sensory-driven decisions and behaviors A postdoctoral position is available in the Wesson lab, supported by a 5 year grant from the NIH/NIDCD, to tackle major questions regarding the olfactory system as they relate to behavior. Particular projects include 1) mechanisms of odor coding within the olfactory cortex, 2) inter-regional coding of odor valence (meaning) by neural ensembles, 3) cellular circuitry underlying odor preferences, and 4) physiological and molecular mechanisms of neurodegeneration in the olfactory system. The lab is well equipped to support investigation of these questions in awake behaving animals in combination with multi-site physiological recordings and chemicogenetic or optogenetic perturbations. The successful candidate will show evidence of research accomplishments, will hold a Ph.D. in a relevant discipline as well as a passion for neuroscience and discovery. Inquiries and application materials (CV) should be sent to Dr. Daniel Wesson, Assistant Professor of Neurosciences, at dww53@case.edu. Case Western Reserve University (http://www.case.edu/) is one of the nation’s largest private universities, with a rich history in biomedical research. The Wesson lab is located within the School of Medicine’s distinguished Department of Neurosciences, which was founded over 20 years ago and has since been home to world leaders in developmental neurobiology, neural regeneration, synaptic physiology, and neurodegeneration. The university is located in Cleveland Ohio, close to numerous parks, Lake Erie, and vibrant neighborhoods. ------------------------------ Daniel W. Wesson, Ph.D. Assistant Professor of Neuroscience & Biology Department of Neurosciences Case Western Reserve University Robbins bldg, E643 (lab) E643D (office) email: dww53@case.edu office: (216)-368-6100 webpage: www.WessonLab.org

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28.08.2015 18:42                   URL #132 A Postdoctoral Research Associate position is available immediately in the Cardiovascular Research Center (CVRC) of Rhode Island Hospital and the Alpert Medical School of Brown University to study the role of cardiac fibroblasts and their crosstalk with myocytes in the cardiac remodeling response to hemodynamic stress and aging. The laboratory of Dr. Mende applies multi-scale approaches at the single cell, bioengineered microtissue, organ and animal level to address clinically relevant questions about G protein-mediated regulation of cardiac hypertrophy, fibrosis and arrhythmia development, using molecular, biochemical, cell biologic and physiological techniques and genetically modified mouse models. The interdisciplinary Cardiovascular Research Center (http://cvrc.brownmedicine.org) is home to scientists, physician-scientists and students investigating molecular mechanisms of cardiac disease, with focal areas in cardiac hypertrophy and failure, ischemia/reperfusion, and arrhythmias. Investigators are supported by Hospital- and Brown-based core facilities. Highly motivated individuals with a PhD, MD or MD/PhD and a background in fibroblast biology, cell signaling and/or cardiac physiology are encouraged to apply. Additional experience with mouse models of cardiac disease and rodent microsurgery is a plus. Applicants should e-mail a curriculum vitae, names and contact information of three references, and a letter stating career goals and research interests to Dr. Ulrike Mende, Professor of Medicine (ulrike_mende@brown.edu). The review of applications will continue until the position is filled. The salary will be based on years of experience, commensurate with NIH guidelines. Rhode Island Hospital is part of Lifespan, an equal opportunity employer; women and minority applicants are encouraged to apply. ----------------------------------------------------------------- Ulrike Mende, MD, FAHA Professor of Medicine Rhode Island Hospital & Alpert Medical School of Brown University 1 Hoppin Street, Providence, RI Phone: (401) 444-9854; E-mail: ulrike_mende@brown.edu

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28.08.2015 18:43                   URL #133 Postdoctoral Associate: Cardiac Signal Transduction and Cellular Biology Laboratory The postdoctoral associate will be a member of the Cardiac Signal Transduction and Cellular Biology Laboratory led by Michael S. Kapiloff, M.D., Ph.D., F.A.H.A., and participate in current research which asks how the formation of multimolecular protein complexes confers specificity in intracellular signaling in cells and in vivo. A major focus of the lab has been the mAKAP scaffold protein that coordinates crosstalk between cAMP, calcium and MAP-kinase signaling pathways and that is important for the induction of cardiac remodeling (http://pediatrics.med.miami.edu/childrens-heart-center/research/cardiac-signal-transduction-and-cellular/). A wide range of techniques are being used to address these questions including the biochemical analysis of recombinant proteins in vitro, culture of primary cardiac myocytes, live cell imaging using novel FRET sensors and the analysis of genetically-modified mouse models. Qualified candidate must possess PhD degree. Experience in molecular biology, biochemistry, and/or cell biology, and especially in vivo cardiac physiology is preferable. Computer proficiency and database knowledge, strong analytical, organizational and communication skills are required. An appropriate combination of education, certifications, and/or relevant work experience will be considered. Michael S. Kapiloff, M.D., Ph.D. Professor of Cardiology, Departments of Pediatrics and Medicine Director, Cardiac Signal Transduction and Cellular Biology Laboratory Interdisciplinary Stem Cell Institute University of Miami Miller School of Medicine Phone: 305-243-7863 (office) 305-243-7864 (lab) Regular Mail: R198 P.O. Box 016960 Miami, FL 33101

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29.08.2015 18:30                   URL #134 An NIH-funded Postdoctoral Fellowship position is available immediately in Dr. Kathleen Morgan’s lab at Boston University to study decoy peptides, targeted by nanoparticles, to break up cytoskeletal linkages that control aortic stiffness and prevent cardiovascular disease with aging. The laboratory uses multidisciplinary approaches to follow aging-associated vascular changes from their molecular and biomechanical origin through their outcomes in aging mouse models. The group is part of the Boston University Affinity Research Collaborative on Aortic Stiffness and the Whitaker Cardiovascular Institute. Individuals with a PhD and/or an MD and solid backgrounds in molecular, physiological, bioengineering or cardiovascular science are encouraged to apply. To apply: e-mail a CV, the contact information of 3 references and a letter describing career goals and research background & skills to Dr. Kathleen Morgan (kmorgan@bu.edu). The review of applications will continue until the position is filled. ---------------------------------------------- Kathleen G. Morgan, PhD Professor of Health Science Sargent College, Boston University 635 Commonwealth Ave. Boston MA 02215 Phone: 617-353-7464

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02.09.2015 18:42                   URL #135 Postdoctoral Training in Cardiovascular and Renal Physiology Cardiovascular-Renal Research Center University of Mississippi Medical Center The Cardiovascular-Renal Research Center at the University of Mississippi Medical Center is currently recruiting postdoctoral fellows to train in cardiovascular and renal research. The Center is an interdisciplinary research program that involves a wide range of basic and clinical research, including genetic, molecular, and cellular mechanisms, and integrative physiology of cardiovascular and renal disease in a variety of animal models. The center currently has over 65 members actively involved in biomedical research. Areas of research emphasis include: renal and molecular mechanisms of hypertension, obesity and metabolic diseases, fetal programming of cardiovascular diseases, gender differences in cardiovascular-renal disease, microcirculation, immune mechanisms in cardiovascular and renal disease, pregnancy and preeclampsia, vascular biology, genetics of hypertension and cardiovascular diseases, stroke, endothelial biology, angiogenesis and neuro-endocrine control of the circulation. Members of the Center receive extramural support from a variety of sources, such as the National Institutes of Health and the American Heart Association. The Center is also funded by a NHLBI Institutional Training Grant entitled "Hypertension and Cardiorenal Diseases Research Training Program". Applicants must have a PhD, MD, or comparable degree. Please send curriculum vitae, a statement of research interests and the names of three references to: Joey P. Granger, Ph.D., Director, Cardiovascular-Renal Research Center at the University of Mississippi Medical Center at jgranger@umc.edu Joey P. Granger, Ph.D. Billy S. Guyton Distinguished Professor Professor of Physiology and Medicine Director, Cardiovascular-Renal Research Center Dean, School of Graduate Studies in Health Scienc

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03.09.2015 17:43                   URL #136 Post-Doc Position Available in Molecular Neuroscience: Spinal Cord Injury A postdoctoral position in Neuroscience is available in the laboratory of Dr. David Schulz in the Division of Biological Sciences at the University of Missouri-Columbia. Our lab combines molecular and electrophysiological approaches to understand neural network plasticity, particularly in motor and autonomic networks. The current project for which the candidate will be responsible is to better understand the impacts of spinal cord injury on autonomic nervous system networks, particularly (but not exclusively) relating to bladder function and dysfunction following injury. We are combining transcriptional profiling and electrophysiological approaches to understand how these bladder control networks are altered by loss of supraspinal input. Interested individuals with a recent PhD in Neuroscience or related fields are encouraged to apply. Previous experience with mammalian electrophysiology and/or molecular approaches are especially desirable, particularly with regards to autonomic nervous system. Our lab also employs multiple model systems, including invertebrate models, and the candidate will have the opportunity to work collaboratively in a multidisciplinary environment. The University of Missouri is located in Columbia, MO, and is the flagship campus of the university system. Columbia is often ranked one of the best college towns in the U.S. and is a vibrant town that is also family-friendly with a very reasonable cost of living. We are committed to ethnic, racial, and gender diversity on our campus and strongly encourage applications from women and members of underrepresented groups. Interested candidates should send CV and names and contact information for 3 references to David Schulz at: schulzd@missouri.edu. Applications will be reviewed in the order received, and the position filled when a suitable candidate is found. Start date is flexible, but the earliest start date will be October 15, 2015. The University of Missouri is an Equal Opportunity/Access/Affirmative Action/Pro Disabled & Veteran Employer ------------------------------ David Schulz Ph.D. Associate Professor University of Missouri Columbia MO ------------------------------

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03.09.2015 17:44                   URL #137 Postdoctoral Position in Cellular Physiology at Emory University, Atlanta, GA. I am seeking a postdoctoral fellow who is creative, curious, and industrious to study the mechanisms underlying muscular dystrophies caused by mutations in the ANO5 (TMEM16E) gene. These include limb-girdle muscular dystrophy type 2L (LGMD2L) (OMIM 611307) and Miyoshi Muscular Dystrophy type 3 (OMIM 613319). ANO5 is a member of a 10-gene family that includes ion channels and phospholipid transporters. We are studying the role of ANO5 in muscle regeneration and repair using genetically engineered immortalized human skeletal muscle cells in culture, skeletal muscle derived from induced pluripotent stem cells from patients, and a mouse model. The applicant should have broad training in cell biology and physiology and an interest in learning and developing new approaches. The position is located in the Department of Cell Biology, Emory University School of Medicine, Atlanta, GA. USA. My website (www.emory.edu/HEARTCELL) is hopelessly outdated because we prefer doing experiments, but a list of our publications is available at http://www.ncbi.nlm.nih.gov/myncbi/browse/...ection/40025553. You can inquire about this position by sending your CV, a paragraph <500 words describing your thoughts about ANO5, and names and email addresses of three references to Criss Hartzell (chartzell.2012@gmail.com). Criss Hartzell Professor Department of Cell Biology Emory University School of Medicine Atlanta, GA 30322

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04.09.2015 16:28                   URL #138 POSTDOCTORAL RESEARCH ASSOCIATE FOCUSED ON CARDIOVASCULAR RESEARCH We seek one or two highly motivated and curious postdoctoral candidates with an interest in vascular cell and translational biology to fill positions on a newly funded NIH grant. The laboratory investigates the role of NADPH oxidases in cell signaling, oxidative stress and disease. Techniques routinely used in the laboratory include Western blotting, qPCR, gene transfer, biochemical and plate-based spectrophotometric and fluorometric assays, FRET, confocal imaging, immunofluorescence and in vivo hemodynamic studies. Self-starters who are resourceful and driven individuals are encouraged to apply. The successful applicant should have extensive expertise in biochemical and molecular biological techniques with a strong track record of publishing success. The fellow will work closely with an interdisciplinary group of scientists at all levels, primarily with basic scientists but also physician-scientists and clinical research personnel in a growing interdisciplinary environment. The emphasis will be on fundamental discovery and/or methodologies applied to drug development and only those with a passion for academic research should apply. Training in models and methods and grant writing will be provided, along with travel to national and international meetings and opportunities for networking with leaders in the field. Candidates must be highly proficient in English (oral and written), possess strong interpersonal skills and a proven desire to develop into independent investigators. If applicable, the offer of employment will be contingent upon obtaining the proper work authorization. Interested candidates should send CVs, a brief cover letter highlighting their career goals and major accomplishments and names and contact information for three references to: Patrick J. Pagano, Ph.D. Professor, The University of Pittsburgh pagano@pitt.edu

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14.09.2015 21:49                   URL #139 Postdoctoral position is available in Dr. Janghoo Lim’s lab in the Department of Genetics and the program in Cellular Neuroscience, Neurodegeneration and Repair at Yale University School of Medicine. We are seeking applicants interested in joining a dynamic and successful team that provides opportunity for individual development as well as collaboration. The main focus of the lab is to determine the molecular basis of cellular pathology in neurodegenerative diseases. In particular, the successful candidate will study the pathogenesis of polyglutamine diseases, including spinocerebellar ataxia type 1 (SCA1) and/or spinal and bulbar muscular atrophy (SBMA). We employ a range of techniques and model systems, including molecular/cell biology, biochemistry, and genetics using cell culture, fly and mouse models. Please see http://medicine.yale.edu/genetics/people/janghoo_lim.profile for detail. The applicant should have experience in molecular/cell biology, biochemistry, neuroscience, and mouse genetics as well as good communication skills. The research environment at Yale is diverse with many opportunities to establish collaborations and interactions with scientists throughout the university. To apply please send to janghoo.lim@yale.edu a brief letter of interest that includes a personal statement outlining your research interests and prior experience, an updated copy of your CV, and contact information for 2-3 references.

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26.09.2015 21:50                   URL #140 A postdoctoral position funded by the NIH is available immediately in Prof. Yi-Ping Li's lab in the Dept. of Integrative Biology and Pharmacology, at the University of Texas Houston Medical School. Prospective candidates will join a research team to study the molecular mechanism of cancer cachexia, a wasting syndrome characterized by muscle wasting. This area of research has been identified by the National Institute of Cancer as one of the "provocative questions". Utilizing cell and molecular biological approaches, the team has been analyzing the signaling mechanism of cancer cachexia using cell culture and animal models (PMC3199382). The current focus of the team is to identify novel tumor-generated factors that serve as the upstream signals activating muscle catabolism, as well as the key catabolic components in muscle cells that mediate tumor-induced muscle wasting. Highly motivated individuals with recent Ph.D. and strong background in modern cell biology and molecular biology are encouraged to apply. Interested individuals should send CV and cover letter via email to yi-ping.li@uth.tmc.edu.

Libra Постоянный участник St.-Petersburg-Houston

27.09.2015 20:25                   URL #141 Postdoctoral Position Available – come join our team! I am seeking a highly motivated, energetic, and a creative postdoctoral fellow to join my team at Vanderbilt University. The overarching goal of the Hasty Laboratory is to determine mechanisms by which obesity increases risk of metabolic diseases such as diabetes and cardiovascular disease. We focus primarily on the role of resident and recruited immune cells in adipose tissue function in the lean and obese states. Applicants should be within 3 years of having received their PhD in Immunology, Physiology, Cell Biology, or similar discipline. Candidate must be able to: work independently, develop new ideas and design their own studies, analyze and interpret their own data, have excellent communication skills (written and oral), and be a team player. Candidates with experience in general immunological techniques such as flow cytometry and/or familiarity with cellular iron handling will be given special consideration. Applicants should contact Alyssa Hasty (Alyssa.hasty@vanderbilt.edu), provide a CV and contact information of individuals who will provide reference letters. Feel free to explore our lab website at https://medschool.vanderbilt.edu/hasty-lab. ------------------------------ Alyssa Hasty, PhD Professor Vanderbilt University Nashville, TN 615-322-5177

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12.11.2021 08:08               URL #143 Senior military officers buried เว็บ123 evidence that British troops were executing detainees in Afghanistan, the High Court has ALLBET been told. Ministry of Defence documents reveal UK Special Forces officers suspected สูตรสล็อตฟรี their men were killing unarmed Afghans who posed no threat. They สูตรบาคาร่า also show the allegations were kept secret and not reported to หวยปิงปอง the Royal Military Police (RMP). The MoD says the evidence is not new and has already been JILI SLOT investigated. The court case follows a 2019 investigation by BBC Panorama and the Sunday PRAGMATIC PLAY Times that raised allegations of unlawful killings by สล็อต123 special forces during the war in Afghanistan. The High Court is considering JOKER GAMING whether the allegations were investigated properly by the armed forces. The man bringing the ปั่นสล็อต case, Saifullah.

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