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 ! slavak4609




  04.12.2013 15:17                   e-mail

: EGFR.gif EGFR- EGFRvIII, . , EGFRvIII , EGFR. EGFR EGFRvIII, , STAT3, STAT3 .

(EGFR) . (GBM) EGFR. , 50% III (EGFRvIII), 2-7, , . EGFR , EGFRvIII .

EGFR EGFRvIII. - , EGFRvIII 58 GBM EGFR. . EGFR EGFRvIII , . EGFR+EGFRvIII , EGFR EGFRvIII.

STAT, , - . EGFR+EGFRvIII -STAT3 -STAT5, EGFR EGFRvIII. , GBM . (EGF) , EGFR+EGFRvIII EGFR, EGFRvIII. EGFRvIII . , EGFR - EGFRvIII.

- EGFR, , (analog-sensitive (as3) alleles). EGFRas3 EGF- EGFRvIII, as3 EGFRas3, EGFRvIII. EGFR+ EGFRvIIIas3 . , EGFR EGFRvIII, . , EGFRvIII EGFR.

, EGFRvIII , . EGFRvIII , STAT . , EGFRvIII STAT-3 EGFR. EGFR+EGFRvIII EGFR STAT .

EGFR STAT GBM, EGFRvIII.


: Fan QW, Cheng CK, Gustafson WC, Charron E, Zipper P, Wong RA, Chen J, Lau J, Knobbe-Thomsen C, Weller M, Jura N, Reifenberger G, Shokat KM, Weiss WA. EGFR Phosphorylates Tumor-Derived EGFRvIII Driving STAT3/5 and Progression in Glioblastoma. // Cancer Cell. 2013; V. 24: P. 438-449.

: EGFR EGFRvIII. EGF EGFR . EGFR EGFRvIII, . EGFRvIII STAT3, STAT3.


   : :    , ": "
04.12.2013 15:18
 ! volmin




  01.12.2019 19:08                   e-mail
      URL #2

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       16.11.2021 15:00              
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       30.11.2021 19:40              
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       30.11.2021 19:43              
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       30.11.2021 19:44              
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       30.11.2021 19:47              
      URL #36

온라인카지노 On the verge of losing his career as a player, Carol surprised fans by signing a contract with Reading, a second-division team. Even the contract was an ultra-short-term contract until
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       30.11.2021 19:48              
      URL #37

메이저사이트 Even if he has been sluggish for a long time, it doesn't make sense for Carol, who once received a lot of attention, to play for only 1.58 million won per week. "The Athletic" said,
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       30.11.2021 19:49              
      URL #38

먹튀검증 In the upcoming transfer market, Reading may propose a contract that can keep Carol after January depending on the size of the release. In the future, Carol's performance and
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       01.12.2021 08:41              
      URL #39

안전놀이터 China's Beijing Guoan announced on the club's official channel the previous day (November 30) that "Cedric Bakambu (30, Congo) will leave the team due to the expiration of his contract
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       01.12.2021 08:42              
      URL #40

메이저놀이터 Bakambu joined FC Sochao Montbelliard in 2010 and joined Beijing Guoan in 2018 after passing through Bursaspor (Turkey) and Villarreal (Spain). According to Sina Sports, he will leave the
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       01.12.2021 08:42              
      URL #41

먹튀검증 However, some analysts say that it is the beginning of the collapse of Chinese soccer as Chinese Super League (first division) clubs have recently faced a major financial crisis.
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       01.12.2021 08:43              
      URL #42

안전놀이터 China, there are reports that players playing in the Super League are not receiving wages on time. As a result, some predict that foreign players' rush to escape will continue.
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       01.12.2021 08:44              
      URL #43

먹튀폴리스 Among them, Beijing Guoan was mentioned as the most representative team that does not pay wages. In addition, teams representing the Super League, such as Guangzhou FC and
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       01.12.2021 08:45              
      URL #44

온라인카지노 The financial situation is difficult, but it is impossible to continue to have expensive foreign players. According to Sina Sports, a Chinese reporter said, "As Bakambu leaves the team,
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       01.12.2021 08:46              
      URL #45

메이저사이트 Beijing Guoan club has written a new history of the team by scoring 58 goals in 87 matches against Bakambu. I always devoted myself to the team. "Our club will remember your
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       01.12.2021 08:47              
      URL #46

먹튀검증 Tottenham sought to leap to the championship competition with the global team, taking advantage of the Union of European Football Associations (UEFA) Champions League
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       02.12.2021 20:08              
      URL #47

안전놀이터 An official from Suwon FC said on the 2nd, "We have been in fierce negotiations with Lee Seung-woo. As a result, an agreement was reached in a large framework for recruiting Lee Seung-woo.
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       02.12.2021 20:10              
      URL #48

메이저놀이터 Lee Seung-woo, a native of FC Barcelona's Hubenille, played for Hellas Verona from 2017 to 2019 following Barcelona B. After moving to Sintrawiden in 2019, he was not given a chance to play.
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       02.12.2021 20:11              
      URL #49

먹튀검증 Last season, Lee Seung-woo, who was on loan for Portimonens, Portugal, suffered more from recent rumors of a transfer. With the remaining contract period remaining, Sint-Truidan played Mongni
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       02.12.2021 20:12              
      URL #50

안전놀이터 because of the news of a sudden transfer negotiation with the K League club in Korea. However, after fierce negotiations with the club, Lee Seung-woo terminated his contract and made a light start.

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