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всего: 99 страницы (5): 1 2 3 4 5 > Голофеевский Фолиант; 2006; 296стр.; ISBN: 5939291392 Фолиант В руководстве приведены современные классификации заболеваний внутренних органов, сопровождаемые клиническими комментариями и примерами формулировок развернутых клинических диагнозов. Кроме того, приведены основные методики терапевтического обследования, которые могут использоваться как в диагностической, так и в медико-социальной и экспертной практике. Для удобства практической работы в приложениях представлены нормативы оценки различных лабораторных показателей. Руководство предназначено, прежде всего, для студентов медицинских вузов (по дисциплинам "факультетская терапия", "госпитальная терапия") и врачей-интернов при изучении внутренней патологии и вопросов экспертной медицины. Руководство также может представлять интерес для широкого круга врачей-специалистов. Заранеее большое спасибо,тем кто прикладывает к поиску книг свои усилия. Zierhut M., Rammensee H., Streilein W. Informa Healthcare; 2007; ISBN: 0849390206 Book Description: In recent years the importance of antigen-presenting cells and their influence on the eyes has been elucidated. We have learned that nearly every structure of the eye harbors these cells, yet they differ in their activities and thus in the ways in which they protect against - or participate in - diseases of the eye. Antigen-Presenting Cells and the Eye summarizes current knowledge about ACPs in general, and their role in the eye, in particular. Laboratory Companion Ред. Gibson I. Wiley-VCH; 1997; 92стр.; ISBN: 352730889X http://www.wiley-vch.de/publish/en/books/bySubjectLS00/ISBN3-527-30889-X<br />http://www3.interscience.wiley.com/cgi-bin/bookhome/119228127 Short description This laboratory companion provides detailed information on the potential, advantages and limitations of this methodology. It presents strategies for choosing targets and delivery systems, allowing selection of the optimum methodology for achieving experimental success with any human or other biological system. For researchers, technicians and advanced graduates in experimental medicine, molecular and cell biology. Review “…recommended for researchers involved in drug discovery.” (The Biotech Journal, April/May 2003) Product Description Antisense and ribozymes have a relatively short yet successful history as research tools in gene expression studies, and thus are considered as having high potential reagents in treating viral infections and cancer. This laboratory companion provides detailed information on the potential, advantages and limitations of this methodology. It critically discusses potential pitfalls, presents strategies for choosing targets and delivery systems, so as to allow the selection of the optimum methodology for achieving fast and reliable experimental success with any human or other biological system. For researchers, technicians and advanced graduates in experimental medicine, molecular and cell biology. CODE http://rapidshare.com/files/132650773/ribozyme.rar Thnx to gigapedia Ред. Crooke S.T. CRC Press; 2007; 848стр.; ISBN: 0849387965 http://www.crcpress.com/shopping_cart/products/product_detail.asp?isbn=9780849387968
Divided into five parts, the book begins with a thorough introduction to the mechanism of antisense drug action including the RNase H mechanism, small RNA silencing pathways, and the potential therapeutics of splice switching oligonucleotides. Leading researchers demonstrate the basics of oligonucleotide therapeutics in part two by delineating medicinal chemistry, pharmacokinetics, and delivery routes such as liposomal formulations for nucleic acid delivery. Part three details hybridization based drugs and considers the dramatic advances represented by 2′ methoxyethyl chimeric antisense inhibitors and duplex RNA drugs. Other chemical classes of drugs and mechanisms of action are described in part four with further discussions on improving the second generation antisense drugs. The final part delves deeply into therapeutic applications. Contributing authors examine the potential of antisense drugs for the alleviation of cardiovascular diseases, metabolic diseases, inflammatory diseases, cancer, neurological disorders, and immune modulation. Presenting a highly detailed, lucid discussion of the remarkable advances in the field, Antisense Drug Technology: Principles, Strategies, and Applications, Second Edition provides the platform for researchers to continue to aggressively pursue the great opportunity represented by this exciting technology. CODE http://ifile.it/65k2h7/crook0849387965.rar or http://rapidshare.com/files/56358907/Crook0849387965.rar Thnx to gigapedia Methods in Molecular Medicine кн.106 Ред. Phillips M.I. Humana Press; 2005; 344стр.; ISBN: 1588292053 http://springer.com/978-1-58829-205-6 A timely primer on the new reality of antisense and RNA inhibition for treating a broad range of diseases. The authors show how antisense oligonucleotides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery. Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous potential to provide a new generation of drugs. Written for: Pharmacologists, pathologists, and biomedical researchers CODE http://ifile.it/jhkbst/phi_ast2emmm.rar or http://rapidshare.com/files/36302972/Antisense_Therapeutics_2nd_ed_1588292053.rar Thnx to gigapedia Methods in Molecular Biology кн.282 Ред. Brady J.M. Humana Press; 2004; 320стр.; ISBN: 0896038734 A collection of cutting-edge techniques for detecting and quantifying apoptosis, understanding its biochemistry, and for identifying the genes and proteins that regulate and carry it out. Described in step-by-step detail, these readily reproducible methods range from flow cytometry and immunohistochemical procedures to kinase activity assays, yeast two-hybrid screening, and the cloning of novel genes by differential expression. The protocols follow the successful Methods in Molecular Biology™ series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. Apoptosis Methods and Protocols constitutes a key technical reference to the significant methodologies used in the field, as well as offering novice and experienced researchers alike powerful tools to illuminate the phenomenon of programmed cell death. Los M., Gibson S.B. Springer-Verlag; 2005; ISBN: 0387233849 Book Description: As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer. Ред. Kirschenbaum D.M. Springer-Verlag; 1972; 319стр.; ISBN: 159124708X, 0306651599 The spectra in this book provide samples of these subtle spectral differences and permit comparisons to be made. This volume should prove useful to a large and varied group including the student who wants to know what a protein spectrum looks like, the researcher who would like to know about the "shift to the red" on removing nucleotide contaminants from a protein, and the analyst seeking to learn where the isosbestic point of a protein in acid and alkali solutions is located. Progress in Brain Research кн.152 Ред. Weaver L., Polosa C. Elsevier Science; 2005; 472стр.; ISBN: 0444519254 http://www.elsevier.com/wps/find/bookdescription.cws_home/707044/description Description Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions. The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions. Audience Spinal cord injury researchers, physicians specializing in spinal cord injury such as neurosurgeons, general practice physicians, physiotherapists, health care providers, emergency room staff of all types, medical students, residents, graduate students in neuroscience. CODE Сейчас здесь: http://ifile.it/ld2g5x3/0444519254.rar pass: autonomic Thnx to gigapedia.org Whitman, Goodfellow, Mpfer, Busse, Trujillo, Ludwig, Suzuki, Parte Springer-Verlag; 2012; 1750стр.; ISBN: 0387682334 Dear colleagues! Can you help me to find this book? Looking forward for your help. Thank you in advance! New Comprehensive Biochemistry кн.35 Ред. Vance D.E., Vance J. Elsevier Science; 2002; 620стр.; ISBN: 044482359X New Comprehensive Biochemistry, Volume 36: Biochemistry of Lipids, Lipoproteins and Membranes, Fourth Edition provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances. Pevsner J. John Wiley & Sons; 2003; 792стр.; ISBN: 0471210048 Wley is proud to announce the publication of the first ever broad-based textbook introduction to Bioinformatics and Functional Genomics by a trained biologist, experienced researcher, and award-winning instructor. In this new text, author Jonathan Pevsner, winner of the 2001 Johns Hopkins University "Teacher of the Year" award, explains problem-solving using bioinformatic approaches using real examples such as breast cancer, HIV-1, and retinal-binding protein throughout. His book includes 375 figures and over 170 tables. Each chapter includes: Problems, discussion of Pitfalls, Boxes explaining key techniques and math/stats principles, Summary, Recommended Reading list, and URLs for freely available software. The text is suitable for professionals and students at every level, including those with little to no background in computer science. Claverie J., Notredame C. John Wiley & Sons; 2007; 436стр.; ISBN: 0470089857 PDF, хорошего качества, ч/б<br />комментарии - http://books.google.ru/books?id=4Tw0aZBnBLEC Очень неплохая книга для студентов/аспирантов, которые хотят быстро познакомиться с биоинформатикой и пользоваться интернет-сервисами анализа сиквенсов, PubMed, Blast, Genebank, swiss-prot, multiple alingment, secondary structure prediction, RNA structure prediction и т.д. На меня произвела очень хорошее впечатление! Подробности о книге - Ред. Barnes M.R. John Wiley & Sons; 2007; 576стр.; ISBN: 0470026197 http://eu.wiley.com/WileyCDA/WileyTitle/productCd-0470026197.html A fully revised version of the successful First Edition, this one-stop reference book enables all geneticists to improve the efficiency of their research. The study of human genetics is moving into a challenging new era. New technologies and data resources such as the HapMap are enabling genome-wide studies, which could potentially identify most common genetic determinants of human health, disease and drug response. With these tremendous new data resources at hand, more than ever care is required in their use. Faced with the sheer volume of genetics and genomic data, bioinformatics is essential to avoid drowning true signal in noise. Considering these challenges, Bioinformatics for Geneticists, Second Edition works at multiple levels: firstly, for the occasional user who simply wants to extract or analyse specific data; secondly, at the level of the advanced user providing explanations of how and why a tool works and how it can be used to greatest effect. Finally experts from fields allied to genetics give insight into the best genomics tools and data to enhance a genetic experiment. Hallmark Features of the Second Edition:
"This book may really help to get geneticists and bioinformaticians on 'speaking-terms'... contains some essential reading for almost any person working in the field of molecular genetics." EUROPEAN JOURNAL OF HUMAN GENETICS "… an excellent resource… this book should ensure that any researcher’s skill base is maintained." GENETICAL RESEARCH Bioinformatics for Geneticists, Second Edition describes the key bioinformatics and genetic analysis processes that are needed to identify human genetic determinants. The book is based upon the combined practical experience of domain experts from academic and industrial research environments and is of interest to a broad audience, including students, researchers and clinicians working in the human genetics domain. CODE Скачать можно тут: http://rapidshare.com/files/34742008/jgt-wbfg.rar Rosenberg A. Springer-Verlag; 1995; 394стр.; ISBN: 0306449749 Abraham Rosenberg assembles the groundbreaking work of preeminent international scientists to provide the most current, state-of-the-art presentation of research in siabiology. This concise volume examines the historical development of the field and reviews current knowledge on the genetic, immunologic, oncologic, neurodevelopmental, pathogenic, and cell regulatory properties of sialic acid. Outstanding features of this work include exhaustive reference material and detailed information tables. The Ultimate Guide to Buying Fake USD: Avoid Scams and Get Quality Counterfeit Money Have you been interested in knowing more about counterfeit currency, be it varying denominations like US Dollars or European Euros? Fascinated by counterfeit CAD bills, perhaps, or the faux British pound? 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The numbers and types of problems being tackled by invasive ablation techniques has been growing dramatically since the mid 1980s, and this publication aims to tie together the aspects of these conditions. Appropriate management of these patients critically depends on knowledge of the type of surgery, the types of arrhythmias these patients are prone to, and the therapeutic modalities that can be used to treat them. Abbas A.K., Lichtman A.H., Pober J.S. W.B. Saunders (now a part of Elsevier Science) ; 2000; 553стр.; ISBN: 0721682332 The 5th Edition of this comprehensive title continues the tradition of delivering an accessible, engaging, and current introduction to this essential subject. The authors describe the principles of basic and applied immunology in a concise, straightforward manner, while incorporating the most up-to-date information. Over 400 illustrations help readers quickly and easily grasp key concepts. The entire text has been revised and includes new information about the organization of lymphoid organs and the mechanisms of innate immunity. |
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