daniil naumoff Постоянный участник Moscow, Russia

14.03.2006 14:28                     URL #1 Предпринят детальный сравнительный анализ всех белков, кодируемых в 203 полностью секвенированных геномах. Среди них - 17 эукариот, 16 архей и 170 эубактерий. Всего было представленно 169 различных видов живых организмов (многие виды оказались представленными несколькими штаммами). Полученные результаты показали, что 67% всех эукариотических белков и 56% прокариотических содержат более одного домена. Каждый из доменов дальнейшему анализу подвергался независимо. Всего проанализировано 633.546 неидентичных белковых доменов. Большинство из них удалось объединить на основе гомологии в 51.778 Gene3D семейств. Только 158.798 доменов оказались невключёнными в семейства. Среди обнаруженных семейств 1.572 ранее были в базе данных CATH (version 2.6), а 7.677 - Pfam (version 18): с учётом перекрывания это в общей сложности около 8 тысяч семейств. Остальные семейства были названы NewFam. Результаты работы позволили авторам предложить список из семи сотен доменов для приоритетного экспериментального определения их пространственных структур. Получение этих данных позволит обладать информацией о строении хотя бы одного представителя из 2.000 наиболее распространённых белковых семейств (строение 1.328 из них уже известно). Эти 2.000 семейств в сумме объединяют 70% всех белковых доменов, включённых в семейства. Увеличение числа семейств до 5.000 позволит повысить уровень покрытия доменов до 80%. Однако, если задаться целью получить экспериментальные данные для одного представителя каждого подсемейства доменов (уровень идентичности не менее 30%), то даже для того, чтобы покрыть наиболее распространённые подсемейства, объединяющие 70% всех доменов, придётся изучить около 90.000 белков, что на нынешнем уровне развития технологий является нереалистичным. Рисунок демонстрирует зависимость процента покрытия белковых доменов от числа наиболее крупных подсемейств, включённых в анализ. По материалам статьи: Marsden RL, Lee D, Maibaum M, Yeats C, Orengo CA. Comprehensive genome analysis of 203 genomes provides structural genomics with new insights into protein family space. Nucleic Acids Res. 2006, 34(3):1066-1080. Pubmed Поблагодарили (13): Alex Vassilevskiy, RODENTIA, NMR_guy, Sandy, ivank, kovzany, Redactor, mpyat, Sofia, Amadeus, Esya, Goose, NBSC Сообщение в колонке новостей, раздел "Наука: общая и молекулярная биология" 14.03.2006 14:44

daniil naumoff Постоянный участник Moscow, Russia

14.03.2006 16:40                       URL #2 Объективности ради надо сказать, что у этой группы недавно была ещё одна статья по той же тематике. Что-то типа предварительного сообщения: Lee D, Grant A, Marsden RL, Orengo C. Identification and distribution of protein families in 120 completed genomes using Gene3D. Proteins. 2005, 59(3):603-615. PubMed

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23.09.2021 12:46               URL #33 If you want to protect your devices from harmful data, go to and download mcafee antivirus.Install mcafee product without any hassle. We provide best installation service ,It protect against virus ,click heremcafeecom-activate.us for more details.Protect your PC from virus, spam, spyware, and malware.Here is the link you need to visit: officecom-setup.us office it the store of office gadgets to make your working smooth and effective.Use of it is in addition principal and the client can get capacity with the utilization of it enough. To setup and install your 123 HP printer go to for mac .For installationprinter123hp.com/setup of drivers, seek help immediately from the website . We’ll help you download the right HP printer software and drivers. Be sure to install cartridges, load paper and power on the printer. The Canon, the famous brand has everything in it's variety starting from their cameras, to cinematography solutions to the scanner as well as printers – each single thing has its own specific productivity.Download from canon.com-ijsetup.net and setup on your device.All you have to do is to activate your Amazon Prime Video on using the activation code you retrieve ...amazon Payment Products. Amazon Rewards Visa Signature Cards; amazon.com-mytv.net Store Card; Amazon Business Card; Amazon Business Line of Credit; Shop with Points.Webroot safe is one of the best antivirus software which provides security from malware and threats.offers full security for your personal information www--webroot.com/safe and banking details is the cheapest antivirus software.

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Guest IP-штамп: frTE90RSShuvo гость

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27.09.2021 13:10               URL #44 We will help you download the correct HP printer software and drivers. Which includes Windows, MacOS, iOS and Android. You can then install your123.hp.com/setup.For installation of drives, you can take help of our website 123.hp.com/setup .A printer driver is software that your computer uses to talk to a physical printer, which may be connected to your computer or another computer on your network. You can download printer drivers and software from our website. You can visit this site to install printer setup. you can take help from our website 123.hp.com/setup.Using a Canon printer service phone, you can get a full installation of the ij.start.canon and go to the installed Canon printer to download the ij.start.canon . To get more and more information, visit our website ij.start.canon and get the information according to convenience .If you want to know more about it then you can visit our website Disneyplus.com/begin and take advantage of it. Click Here for the DisneyPlus.com Login: Sign In to Disney+ If you’ve been using Disney Plus on your iPhone or Samsung TV but now want to use it on your TV, then you need to know the disneyplus.com/begin page. Thankfully, it’s super easy to get to, and I’ve got all the details for you below. Here’s How to Use disneyplus.com/begin Canon ijsetup CD is not the well-suited Canon.com/ijsetup technique to use setup installation for longer. One can also install from anther origin if your device is having issues in the online installation or any otherCanon.com ijsetup - Before knowing canon.com/ijsetup about the process to connect the printer to the computer or other devices, we can see about the canon ij setup.

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27.09.2021 13:48               URL #45 Using a Canon printer service phone, you can get a full installation of the Canon.com/ijsetup and go to the installed Canon printer to download the ij.start.canon .To get more and more information, visit our websiteCanon.com/ijsetup and get the information according to convenience .To setup and install your 123 HP printer go to 123.hp.com/setup for mac . For installation of drivers, seek help immediately from the website 123.hp.com/setup. We’ll help you download the right HP printer software and drivers. Be sure to install cartridges, load paper and power on the printer. Download the 123.hp.com/setup to get the recommended software for your printer. Disney Plus is one of the most popular streaming services in the world right now. You can go to Disneyplus.com/begin and activate your disney now for watching TV shows and movie ,you can also play games. you can also Disnetplus.com/begin to watch disney channel With which you can watch full episodes of your favorite Disney Junior and Disney XD shows .

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27.09.2021 13:48               URL #46 Using a Canon printer service phone, you can get a full installation of the Canon.com/ijsetup and go to the installed Canon printer to download the ij.start.canon .To get more and more information, visit our websiteCanon.com/ijsetup and get the information according to convenience .To setup and install your 123 HP printer go to 123.hp.com/setup for mac . For installation of drivers, seek help immediately from the website 123.hp.com/setup. We’ll help you download the right HP printer software and drivers. Be sure to install cartridges, load paper and power on the printer. Download the 123.hp.com/setup to get the recommended software for your printer. Disney Plus is one of the most popular streaming services in the world right now. You can go to Disneyplus.com/begin and activate your disney now for watching TV shows and movie ,you can also play games. you can also Disnetplus.com/begin to watch disney channel With which you can watch full episodes of your favorite Disney Junior and Disney XD shows .

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27.09.2021 13:56               URL #47 To setup and install your 123 HP printer go to 123.hp.com/setup for mac . For installation of drivers, seek help immediately from the website 123.hp.com/setup. We’ll help you download the right HP printer software and drivers. Be sure to install cartridges, load paper and power on the printer. Download the Disneyplus.com/begin to get the recommended software for your printer. Click Here for the DisneyPlus.com Login: Sign In to Disney+ If you’ve been using Disney Plus on your iPhone or Samsung TV but now want to use it on your TV, then you need to know the Disneyplus.com/begin page. Thankfully, it’s super easy to get to, and I’ve got all the details for you below. Here’s How to Use disneyplus.com/begin .Download the 123.hp.com/setup to get the recommended software for your printer.

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27.09.2021 14:04               URL #48 To setup and install your 123 HP printer go to 123.hp.com/setup for mac . For installation of drivers, seek help immediately from the website 123.hp.com/setup. We’ll help you download the right HP printer software and drivers. Be sure to install cartridges, load paper and power on the printer. Download the 123.hp.com/setup to get the recommended software for your printer. Disney Plus is one of the most popular streaming services in the world right now. You can go to Disneyplus.com/begin and activate your disney now for watching TV shows and movie ,you can also play games. you can also Disneyplus.com/begin to watch disney channel With which you can watch full episodes of your favorite Disney Junior and Disney XD shows .

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28.09.2021 07:41               URL #49 Hulu is a streaming device, lets you watch thousands of paid & free video content on your TV screen via the Internet. It allow its users to add channels and download movies and much more at one place. All you need to redeem hulu activation code through which you can easily get started. Hulu activation code is an alphanumeric code used to activate hulu devices. Visit: hulu.com/activate and enter hulu activation code to activate your hulu account.The need for a reliable antivirus like Norton Enrollment is increasing, you can download it by visiting the website Norton.com/setup Not only companies as a measure of data security, but everyone is now relying on antivirus programs that can be found on the norton.com/setup with product key page. If you have any problem you can visit our website norton.com/setup and get help.The Amazon My TV Code program requires the customer to have an Amazon account and a streaming device or TV.Amazon.com/mytv Amazon Prime Video is available on almost all streaming devices like Roku, Amazon Fire TV, Chromecast. For this you just have to go to Amazon and activate amazon with the help of You can visit our website Amazon.com/code for details of the entire process.Mcafee antivirus acts as a shield of the device. It protects against viruses, malware, online threats etc. You can download, install and activate mcafee.com/activate with activation code. mcafee antivirus provides protection from viruses, hackers, spyware and more harmful websites. If you want to protect your devices against harmful data, download mcafee antivirus by visiting the mcafee.com/activate website

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28.09.2021 07:49               URL #50 In Hulu you will get normal susbcription and limited channels to visit however in Hulu plus is addtional version of hulu in which more TV shows and movies are added. You will find latest series such as game of throne. You can watch full movies and seasons instead only 5 to 6 episodes. You can watch hulu on your computer devices as well. To activate hulu code you need to enter hulu activation code on hulu.com/activate. Before activating login in to your hulu account with the credentials which you registered.If you want to know more about it then you can visit our website Disneyplus.com/begin and take advantage of it. Click Here for the DisneyPlus.com Login: Sign In to Disney+ If you’ve been using Disney Plus on your iPhone or Samsung TV but now want to use it on your TV, then you need to know the disneyplus.com/begin page. Thankfully, it’s super easy to get to, and I’ve got all the details for you below. Here’s How to Use disneyplus.com/begin. The Amazon My TV Code program requires the customer to have an Amazon account and a streaming device or TV. Amazon Prime Video is available on almost all streaming devices like Roku, Amazon Fire TV, Chromecast. All you have to do is go to and activate Primevideo.com/mytv with the help of Amazon's activation code. You can visit our website amazon.com/mytv for details of the entire process.To register your device on the Amazon website you go to our website and enter the given code.The Canon, the famous brand has everything in it's ij.start.canon variety starting from their cameras, to cinematography solutions to the scanner as well as printers – each single thing has its own specific productivity. the user can set up the Canon ij.start.canon Printer Model. When you do connect the Canon printer into your pc, your system does not need to install the driver on it.Amazon Instant Amazon.com/mytv Video application on your LG TV or Blu-ray Player and then Prime Instant Video to start watching. Amazon.com mytv is amazon.com/mytv a registration portal of Amazon Prime from which members can watch thousands of movies and TV shows The instant video amazon.com/mytv servicecan only be watched after registering your device with a simple subscription code.

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