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. . AML , , . . AML . (~250 ) 103 , - AML. AML - (DNMT3Amut) ARF/p53 NPM1 (NPM1). - NPM1 . ( 12 ) , DNMT3Amut. NPM1 . AML . DNMT3Amut , . DNMT3Amut, NPM1. DNMT3Amut. , AML, , DNMT3Amut. HSCs. DNMT3Amut. . , - AML HSCs, DNMT3Amut. , . , - HSCs HSCs . , DNMT3A HSCs AML. AML NPM1 (NPM1), . . HSCs, , AML. , - HSCs, . , DNMT3A . AML . : Shlush LI, Zandi S, Mitchell A, Chen WC, Brandwein JM, Gupta V, Kennedy JA, Schimmer AD, Schuh AC, Yee KW, McLeod JL, Doedens M, Medeiros JJ, Marke R, Kim HJ, Lee K, McPherson JD, Hudson TJ; HALT Pan-Leukemia Gene Panel Consortium, Brown AM, Trinh QM Stein LD, Minden MD, Wang JC, Dick JE. : (%) DNMT3Amut NPM1 (AML) - AML. 0-100 . , ": " 02.04.2014 07:48 |
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