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guest: ППГ IP-штамп: frFFhKp0FboeE гость |
Published Online June 2015 in SciRes. How to cite this paper: Gariaev, P.P. (2015) Another Understanding of the Model of Genetic Code Theoretical Analysis. Open Journal of Genetics, 5, 92-109. Another Understanding of the Model of Genetic Code Theoretical Analysis Petr Petrovich Gariaev Institute of Quantum Genetics LLC, Moscow, Russia Email: gariaev@mail.ru Received 16 May 2015; accepted 27 June 2015; published 30 June 2015 Copyright © 2015 by author and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). Abstract At present the model of the genetic code (the code of protein biosynthesis) proposed almost 50 years ago by M. Nirenberg and F. Crick has undergone severe erosion. Tactically, it is true that triplicity and the synonymous degeneracy are unmistakable. But the Nirenberg-Crick postulate about unambiguous coding of amino acids, i.e., the strategy raises reasonable doubt. The reasons to doubt showed up very early: it turned out that the triplet UUU codes both phenylalanine and leucine, which was inconsistent with the declaration of the unambiguity of the DNA-RNA encoding of amino acids in proteins. On the other hand, the ambiguity automatically stems from the Wobble Hypothesis by F. Crick relating to the wobbling of the third nucleotide in codons, (random, undetermined behavior), which means the 3’-5’ codon-anticodon pair is not involved in the encoding, and represents a “steric crutch”. In fact, amino acids are coded not by triplet, but by doublet of nucleotides in a triplet, according to “Two-out-of-Three” rule by Ulf Lagerkvist. From this perspective, the codon families split into two classes: 32 codon-synonym triplets and 32 codon triplets with undetermined coding functions, that is inherent to one of the 32 codons UUU. These “undetermined” codons have called homonyms. They are ambiguous as they potentially and simultaneously encode two different amino acids, or amino acid and the stop function. However, the ambiguity is overcome in real protein biosynthesis. This is due to the sign orientations of ribosomes within mRNA contexts. This is the way the semantics of the codon-homonyms occur, as an exact analogy of the consciousness work in the human languages, abounding with homonyms. This turn in the understanding of the protein code, as actual text formation, leads to a strong idea of the genome as a quasi-intelligent biocomputer structure of living cells. Ignoring this leads to erroneous and dangerous works of genetic engineering, the most important results are Synthia bacteria with synthetic genome and GM foods. Protein biosynthesis is a key, but not the only basic information function of chromosomes. There are other, no less important, holographic and quantum non-locality functions related to morphogenesis. In this plane, the work of the genome, as a quantum biocomputer, occurs on the wave level. Here the main function is regulatory quantum broadcasting of genetic-metabolic information on the intercellular, tissue and organism levels using a coherent photon DNA radiation and its nonlinear vibrational states (sound). DNA information presents it ***************************
сейчас текст сообщения виден только автору и модераторам; все остальные посетители увидят его только после утверждения модератором (письмо-уведомление модератору отправлено); автор сообщения МОЖЕТ редактировать текст ещё до утверждения |
guest: П.Гаряев IP-штамп: frFFhKp0FboeE гость |
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Guest IP-штамп: frZJRuYITSSWo гость |
Плюс Do SCIRP journals have Impact Factors? A1: The journal impact factor (JIF) normally referred to is the proprietary journal impact factor from Thomson Reuters calculated based on the Web of Science (WOS) and published in the Journal Citation Reports® (JCR). We call this the JCR®JIF. No, none of SCIRP's journals have presently a JCR®JIF, but many of our journals have currently been accepted for Impact Factor tracking by Thomson Reuters (ISI). Please see our analysis from 05/2013. Please also consider the information given in the San Francisco Declaration on Research Assessment (DORA) which is also copied into SCIRP's News. Плюс никто ее и читать не будет |
Guest IP-штамп: frFFhKp0FboeE гость |
А по сути ответить, как? Или слабО? |
Guest IP-штамп: frFFhKp0FboeE гость |
(Guest @ 26.07.2015 19:14) Большое достижение тиснуть статью в журнал из разряда "печатаем все что пришлют" ":) Плюс Плюс никто ее и читать не будет А почему такая самоуверенность? Правда, она роднит с таковой Нобелиата Ниренберга, допустившего грубый просмотр собственных же результатов по неоднозначному кодированию одного из кодонов-омонимов (UUU), когда он экспериментально продемонстрировал, что UUU одновременно (!) кодируют разные аминокислоты - ФАЛ и ЛЕЙ. Это было потенциально огромное открытие, а он с Криком написал "молекулярная природа этого нам не понятна" (!). Раз непонятна, тогда зачем постулировать "однозначность" кодирования аминокислот. В общем, позор для мол. биологии и генетики. А сейчас расхлёбываем кашу из ГМ зерна. |
guest: П.Гаряев IP-штамп: frFFhKp0FboeE гость |
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