, . , - SR-AI: "The 451 residue polypeptide of human SR-AI can be subdivided into six regions: ... , the extracellular domain comprising of alpha-helical coiled-coils, ...".
The possibility of coiled coils for α-keratin was initially somewhat controversial. Linus Pauling and Francis Crick independently came to the conclusion that this was possible at about the same time. In the summer of 1952, Pauling visited the laboratory in England where Crick worked. Pauling and Crick met and spoke about various topics; at one point, Crick asked whether Pauling had considered "coiled coils" (Crick came up with the term), to which Pauling said he had. Upon returning to the United States, Pauling resumed research on the topic. Streamen
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