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(3):  1 2 3 > 
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  29.11.2013 14:30                   e-mail

: CSF.png . , , . . , , . , , , .

, . , .

(glioblastoma multiforme, GBM) . , , GBM.

Novartis BLZ945 , GBM GBM. BLZ945 CSF-1R. , GBM BLZ945 . 2,5 GBM 64,3% 26 . 8 . GBM , BLZ945 . 9-17 . BLZ945 GBM , .

, CSF-1R- . , BLZ945. , GBM , BLZ945 . , . , , CSF-1R. GM-CSF IFN-γ.

, CSF-1R , , BLZ945 . 257 : 52 , 205 . : , . 2, , , . , BLZ945 2 .

BLZ945 GBM , . , BLZ945 .

CSF-1R GBM BLZ945. , GBM, .


: Pyonteck SM, Akkari L, Schuhmacher AJ, Bowman RL, Sevenich L, Quail DF, Olson OC, Quick ML, Huse JT, Teijeiro V, Setty M, Leslie CS, Oei Y, Pedraza A, Zhang J, Brennan CW, Sutton JC, Holland EC, Daniel D, Joyce JA. CSF-1R inhibition alters macrophage polarization and blocks glioma progression. // Nat Med. 2013; V. 19: P. 1264-1272.

: .
a. CSF-1 .
b. CSF-1 - CSF-1R . .

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       30.11.2021 20:09              
      URL #37

안전놀이터 Even after coming to EPL, Carol showed a good performance of 11 goals and 10 assists in 19 games. Less than a year after being promoted, Carol chose to transfer, resulting in a career
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       30.11.2021 20:10              
      URL #38

먹튀폴리스 At that time, Liverpool needed a substitute as Fernando Torres suddenly left for Chelsea. Liverpool decided to bring Carol and invested 41 million euros (about 55.1 billion won).
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       30.11.2021 20:11              
      URL #39

온라인카지노 On the verge of losing his career as a player, Carol surprised fans by signing a contract with Reading, a second-division team. Even the contract was an ultra-short-term contract until
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       30.11.2021 20:12              
      URL #40

메이저사이트 Even if he has been sluggish for a long time, it doesn't make sense for Carol, who once received a lot of attention, to play for only 1.58 million won per week. "The Athletic" said,
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       30.11.2021 20:13              
      URL #41

먹튀검증 In the upcoming transfer market, Reading may propose a contract that can keep Carol after January depending on the size of the release. In the future, Carol's performance and
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       01.12.2021 08:18              
      URL #42

안전놀이터 China's Beijing Guoan announced on the club's official channel the previous day (November 30) that "Cedric Bakambu (30, Congo) will leave the team due to the expiration of his contract
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       01.12.2021 08:19              
      URL #43

메이저놀이터 Bakambu joined FC Sochao Montbelliard in 2010 and joined Beijing Guoan in 2018 after passing through Bursaspor (Turkey) and Villarreal (Spain). According to Sina Sports, he will leave the
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       01.12.2021 08:20              
      URL #44

먹튀검증 However, some analysts say that it is the beginning of the collapse of Chinese soccer as Chinese Super League (first division) clubs have recently faced a major financial crisis.
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       01.12.2021 08:21              
      URL #45

안전놀이터 China, there are reports that players playing in the Super League are not receiving wages on time. As a result, some predict that foreign players' rush to escape will continue.
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       01.12.2021 08:22              
      URL #46

먹튀폴리스 Among them, Beijing Guoan was mentioned as the most representative team that does not pay wages. In addition, teams representing the Super League, such as Guangzhou FC and
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       01.12.2021 08:23              
      URL #47

온라인카지노 The financial situation is difficult, but it is impossible to continue to have expensive foreign players. According to Sina Sports, a Chinese reporter said, "As Bakambu leaves the team,
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       01.12.2021 08:25              
      URL #48

메이저사이트 Beijing Guoan club has written a new history of the team by scoring 58 goals in 87 matches against Bakambu. I always devoted myself to the team. "Our club will remember your
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       01.12.2021 08:26              
      URL #49

먹튀검증 Tottenham sought to leap to the championship competition with the global team, taking advantage of the Union of European Football Associations (UEFA) Champions League
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       01.12.2021 13:14              
      URL #50

안전놀이터 Makanday is a young prospect born in 2001 and has grown up through Tottenham Youth Academy since childhood. He joined the U-18 team from the 2017-18 season and has been promoted

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