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всего: 872 страницы (44): 1 2 3 4 5 > » Ред. Link A.J. Humana Press; 1998; 608стр.; ISBN: 0896035247 A step-by-step tour through the complete process of doing proteomics. With easy-to-follow instructions, complete with many helpful hints and explanations, leading investigators and pioneers in the field show how to make protein extracts, reproducibly run them on 2-D gels, detect them, analyze the data, and precisely identify each protein. The book covers the latest methods of using carrier ampholytes in the 1st dimension, casting and running immobilized pH gradient 2-D gels, MALDI-TOF-based peptide mapping, automated tandem mass spectrometry, and nanoelectrospray ionization technology. For the 2nd dimension, there are methods for running flatbed or vertical gels and for protein detection using autoradiography, and Coomassie, silver, and reversible metal-chelate stains. 2-D Proteome Analysis Protocols is the most complete guide for using proteomics to answer biological questions. Shapiro T.W., Davison D.B., Rust D.M. Jones and Bartlett Publishers; 1997; 454стр.; ISBN: 076370217X Book Description ...bone marrow transplantation clinicians can use this handbook for bedside use...includes information on symptom management, pre-transplant evaluation, and long-term follow up. Book Info Univ. of Arizona,Tucson.Pocket-sized, quick reference in outline format. Practical handbook for clinicians working with adult and pediatric bone marrow transplantation patients. Trim size: 6 x 4 inches. Dennison C. Kluwer Academic Publishers; 2002; 195стр.; ISBN: 0792357515 This text takes the reader on a guided tour through the philosophical and physical foundations of protein isolation. Aimed at a student readership, it will also be very useful to life science researchers faced with the task of isolating a protein for the first time. The logic of the overall approach to isolating a protein is explained and the physical principles of each separation method are made clear by the use of simple models and analogies, drawn from everyday experiences. The author's aim has been to deepen the readers' insight into protein isolation methods, so that they may tackle new problems and perhaps devise new approaches to old problems. Many of the methods described are drawn from the author's own research and are thus uniquely described here: examples are three-phase partitioning, non-linear electrophoresis, and a simple approach to buffer making. Everitt B.S. CRC Press; 2001; 256стр.; ISBN: 1584882808 Review For those who...find learning by example to be efficient and effective, the book is a worthwhile investment. …useful as a way for students or applied statisticians to get up to speed quickly on using S-Plus. …The book has several strengths: It is well organized and easy to read; The examples cover a broad range of standard statistical methods, and are general enough to be understood by readers from a variety of disciplines; At the same time, the examples are involved enough to provide substantive engagement with the software ...There is enough statistical background to flesh out the examples, but not so much that the emphasis on learning the software is lost.…This volume is a worthwhile investment for students or statisticians who want to improve their facility with S-Plus and who learn well from examples. - The American Statistician. Judith Manola, Dana-Farber Cancer InstituteThe book does a nice job working with the biggest differentiator for S-PLUS … the book really works best to help persons familiar with statistical tools as they get started on analyses using S-Plus.- Eric R. Ziegel, Technometrics, August 2002 Book Description The second edition of this popular handbook has been fully updated to provide an outstanding introduction to the S-PLUS statistical software package for the entire spectrum of users, from students to applied statisticians. The author uses both the command language approach and the graphical user interface throughout the book and includes data sets from a variety of disciplines, such as medicine, finance, sports, and epidemiology. Exercises with suggested answers and clear engaging prose from a well-established author/statistician make the updated Handbook of Statistical Analyses Using S-Plus ideal both as a reference and for undergraduate and graduate courses in data analysis. Fox S. 2002; 448стр.; ISBN: 0072440872 The laboratory experiences provided in this manual allow students to become familiar, in a way that cannot be achieved by lecture and text alone, with many fundamental concepts of physiology. Clinically-oriented lab exercises heighten student interest and demonstrate the health applications of physiology. Each lab is designed to provide hands-on experience in applying physiological concepts, and requires active participation to carry out the procedures and collect data, as well as critical thinking skills to answer the questions at the end of each exercise. The manual is self-contained, so students can prepare for the laboratory exercises and quizzes without having to refer to the textbook. Feibelman P.J. Addison-Wesley and Benjamin Cummings; 1994; 109стр.; ISBN: 0201626632 Book Info Offers sound advice on selecting a thesis or postdoctoral adviser, choosing among research jobs in academia, government laboratories, and industry, preparing for an employment interview, and defining a research program. DLC: Science - Vocational guidance. --This text refers to an out of print or unavailable edition of this title. Ред. Berrar D.P., Dubitzky W., Granzow M. Springer-Verlag; 2002; 384стр.; ISBN: 1402072600 Book Description A Practical Approach to Microarray Data Analysis is for all life scientists, statisticians, computer experts, technology developers, managers, and other professionals tasked with developing, deploying, and using microarray technology including the necessary computational infrastructure and analytical tools. The book addresses the requirement of scientists and researchers to gain a basic understanding of microarray analysis methodologies and tools. It is intended for students, teachers, researchers, and research managers who want to understand the state of the art and of the presented methodologies and the areas in which gaps in our knowledge demand further research and development. The book is designed to be used by the practicing professional tasked with the design and analysis of microarray experiments or as a text for a senior undergraduate- or graduate level course in analytical genetics, biology, bioinformatics, computational biology, statistics and data mining, or applied computer science. Key topics covered include: -Format of result from data analysis, analytical modeling/experimentation; -Validation of analytical results; -Data analysis/Modeling task; -Analysis/modeling tools; -Scientific questions, goals, and tasks; -Application; -Data analysis methods; -Criteria for assessing analysis methodologies, models, and tools. Book Info Univ. of Ulster, Coleraine, Northern Ireland. Text provides information on the use of microarray technology, including the necessary computation infrastructure and analytical tools. Addresses the requirements of professionals to gain a basic understanding of microarray analysis methodologies and tools. Written in expanded-outline format. A Student Handbook for Writing in Biology, Third Edition Knisely, Karin A user's guide to the human genome; Nature Genetics supplement Tyra G Wolfsberg, Kris A Wetterstrand, Mark S Guyer, Francis S Collins & Andreas D Baxevanis Nature Publishing Group/Macmillan Online Publishing; 2002; pp82 The primary aim of A User’s Guide to the Human Genome is to provide the reader with an elementary hands-on guide for browsing and analyzing data produced by the International Human Genome Sequencing Consortium and other systematic sequencing efforts. The majority of this supplement is devoted to a series of worked examples, providing an overview of the types of data available, details on how these data can be browsed, and stepby- step instructions for using many of the most commonly-used tools for sequence-based discovery. The major web portals featured throughout include the National Center for Biotechnology Information Map Viewer, the University of California, Santa Cruz Genome Browser, and the European Bioinformatics Institute’s Ensembl system, along with many others that are discussed in the individual examples. It is hoped that readers will become more familiar with these resources, allowing them to apply the strategies used in the examples to advance their own research programs. A user's guide to the human genome; Nature Genetics supplement Tyra G Wolfsberg, Kris A Wetterstrand, Mark S Guyer, Francis S Collins & Andreas D Baxevanis Nature Publishing Group/Macmillan Online Publishing; 2002; pp82 http://rapidshare.de/files/3544342/A_user_...genome.pdf.html Avdeef A. 2003; 312стр.; ISBN: 0471423653 Review “...a useful book for anyone interested in the measurement of physiochemical parameters that relate to drug permeability.”(Journal of Medicinal Chemistry, Vol. 47, No. 7) "...useful compilations of data...of use to those working in the agrochemical and environmental industries..." (Chemistry & Industry, 19 January 2004) Review “...a useful book for anyone interested in the measurement of physiochemical parameters that relate to drug permeability.”(Journal of Medicinal Chemistry, Vol. 47, No. 7) "...useful compilations of data...of use to those working in the agrochemical and environmental industries..." (Chemistry & Industry, 19 January 2004) [b] http://rapidshare.de/files/3544416/Absorpt...opment.pdf.html Brimblecombe P., Hara H., Houle D., Novak M. Springer-Verlag; 2007; 420стр.; ISBN: 1402058845 Book Description Acid rain is still with us. Although it is a problem that people have worked diligently to solve, there are still many problem areas throughout the world. In reality the focus of acid rain research has shifted, and this book adds new vision to the topic. It contains papers, selected from Acid Rain 2005, the 7th International Conference on Acid Deposition, that take a broad perspective of the issues, emphasizing a number of themes: - the emission, concentration and deposition of pollutants - nitrogen and trace elements in ecosystems and their effects on forests, water and soil - studies of material damage and recovery - critical loads The book is aimed at scientists and researchers who are working in the area of acid rain and its effects, and on nutrient cycling. This latest research will be of value to those concerned with the mitigation of acid rain effects. Ред. Foote C.S. Blackie Academic & Professional; 1995; 342стр.; ISBN: 0751402923 Book Description Taking an interdisciplinary approach, this book and its counterpart, Active Oxygen in Biochemistry, explore the active research area of the chemistry and biochemistry of oxygen. Complementary but independent, the two volumes integrate subject areas including medicine, biology, chemistry, engineering, and environmental studies. Book Info Explores the active research area of the chemistry and biochemistry of oxygen. Surveys oxidation activation in key biological systems. Ред. Foote C., Valentine J.S., Greenberg A., Liebman J.F. Springer-Verlag; 1995; 360стр.; ISBN: 0412034417 Book Description Taking an interdisciplinary approach, this book and its counterpart, Active Oxygen in Biochemistry, explore the active research area of the chemistry and biochemistry of oxygen. Complementary but independent, the two volumes integrate subject areas including medicine, biology, chemistry, engineering, and environmental studies. Book Info Explores the active research area of the chemistry and biochemistry of oxygen. Surveys oxidation activation in key biological systems. --This text refers to the Hardcover edition. Methods in Molecular Medicine кн.21 Ред. Wold W.S. Humana Press; 1998; 368стр.; ISBN: 0896035514 A cutting-edge collection of readily reproducible methods for conducting research with adenoviruses, the premier and most widely used model in cell and molecular biology. The methods range from how to grow and titer adenoviruses and how to construct specific alterations in the adenovirus genome, to how to measure apoptosis induced by cells of the immune system, cytokines, and intrinsic apoptosis effectors. In addition, there are methods to study transcription and splicing with in vitro systems and for the adenovirus-mediated transformation of cells to a malignant state. Each method is written by a prominent investigator well-versed in the technique and includes a brief background discussion and tried, as well as true step-by-step instructions. Methods in Molecular Medicine кн.130 Wold W.S., Tollefson A.E. Humana Press; 2007; 241стр.; ISBN: 1588295982 Review Reviews of the First edition: "This book caters quite well to those who simply want to grow adenoviruses, assay them, and use them. . .a very comprehensive methods book that will be a laboratory standard for years to come."-Microbiology Today ". . .this book constitutes an excellent reference text . . .this book is replete with useful information for both the virologist and the non-virologist who is interested in working with adenoviruses."-FEBS Letters Book Description Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study. In addition to updating and expanding important chapters from the first edition, the authors have added new chapters that address innovative, exciting areas of emphasis in Ad research, including Ad vector construction and use, real-time PCR, use of new animal models, and methods for quantification of Ad virus or virus expression/interactions. Each of the protocols presented in these volumes is written by trendsetting researchers in their respective areas of expertise. Volume 1 addresses several important techniques for construction of adenoviruses for use as vectors and for basic research. Highlighted topics include deletion mutants, capsid modifications, insertions, and gene replacements in human, murine, bovine, and ovine adenoviruses. In Volume 2, the authors focus on methods that elucidate and quantitate the interactions of Ad with the host. Each of the protocols in these volumes provides a general introduction, followed by tried-and-true step-by-step methods. Both novice and experienced researchers will reap tremendous benefit from these groundbreaking volumes in Ad research. Methods in Molecular Medicine кн.131 Wold W.S., Tollefson A.E. Humana Press; 2007; 362стр.; ISBN: 1588299015 Review Reviews of the First edition: "This book caters quite well to those who simply want to grow adenoviruses, assay them, and use them. . .a very comprehensive methods book that will be a laboratory standard for years to come."- Microbiology Today ". . .this book constitutes an excellent reference text . . .this book is replete with useful information for both the virologist and the non-virologist who is interested in working with adenoviruses."-FEBS Letters Book Description Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study. In addition to updating and expanding important chapters from the first edition, the authors have added new chapters that address innovative, exciting areas of emphasis in Ad research, including Ad vector construction and use, real-time PCR, use of new animal models, and methods for quantification of Ad virus or virus expression/interactions. Each of the protocols presented in these volumes is written by trendsetting researchers in their respective areas of expertise. Volume 1 addresses several important techniques for construction of adenoviruses for use as vectors and for basic research. Highlighted topics include deletion mutants, capsid modifications, insertions, and gene replacements in human, murine, bovine, and ovine adenoviruses. In Volume 2, the authors focus on methods that elucidate and quantitate the interactions of Ad with the host. Each of the protocols in these volumes provides a general introduction, followed by tried-and-true step-by-step methods. Both novice and experienced researchers will reap tremendous benefit from these groundbreaking volumes in Ad research. Methods in Molecular Biology кн.96 Ред. Dejana E., Corada M. Humana Press; 1999; 240стр.; ISBN: 0896032589 An international corps of expert investigators describe their optimized techniques for both the identification of new cell adhesion proteins and for the characterization of novel adhesive structures. Their cutting edge methods will enable both novice and experienced researchers readily to identify and clone new adhesion proteins, to successfully produce inhibitors of the adhesive activity, to develop biological models for the assay of cell-to-matrix and cell-to-cell adhesion in vitro, and to measure the signaling activities of adhesion proteins. By illuminating these adhesive molecules and the possibilities for manipulating them, the new experimental strategies collected here will have considerable clinical potential for the regulation of immunity, inflammation, tissue remodeling, and embryonic development. Methods in Molecular Biology кн.126 Machida C.A. Humana Press; 1999; 592стр.; ISBN: 0896036022 Curtis Machida and a panel of expert investigators present a comprehensive collection of modern molecular methods for analyzing adrenergic receptors and corresponding second messenger systems. These proven and readily reproducible techniques utilize genetic, RNA, protein expression, transactivator, and second messenger methodologies, as well as immunocytochemical, electrophysiological, transgenic, and in situ hybridization approaches. Each of the experts writing here details the use of their chosen method in examining the adrenergic receptor system, using aspects of the genetic flow of information as a guide: DNA ‘ RNA ‘ transactivator ‘ protein expression ‘ second messenger analyses ‘ cellular analyses ‘ transgenic whole animal approaches. Comprehensive and rich in practical detail, Adrenergic Receptor Protocols provides the first collection of readily reproducible methods for the study of these important regulators of CNS-mediated behavior and neural functions. Yang R. 2003; 424стр.; ISBN: 0471297410 Review "…a very good book on a very important topic. Well-written, resplendent with figures and tables, and well-referenced are some of my observations." (Journal of Hazardous Materials, 109, 2004) "...fulfils existing demand for a simple and comprehensive text devoted to commercial and novel adsorbents...a valuable guide..." (Journal of the American Chemical Society, Vol. 125, No. 39, 2003) Book Description Adsorption promises to play an integral role in several future energy and environmental technologies, including hydrogen storage, CO removal for fuel cell technology, desulfurization of transportation fuels, and technologies for meeting higher standards on air and water pollutants. Ralph Yang's Adsorbents provides a single and comprehensive source of knowledge for all commercial and new sorbent materials, presenting the fundamental principles for their syntheses, their adsorption properties, and their present and potential applications for separation and purification. Chapter topics in this authoritative, forward-looking volume include: - Formulas for calculating the basic forces or potentials for adsorption - Calculation of pore-size distribution from a single adsorption isotherm - Rules for sorbent selection - Fundamental principles for syntheses/preparation, adsorption properties, and applications of commercially available sorbents - Mesoporous molecular sieves and zeolites -?-complexation sorbents and their applications - Carbon nanotubes, pillared clays, and polymeric resins Yang covers the explosion in the development of new nanoporous materials thoroughly, as the adsorption properties of some of these materials have remained largely unexplored. The whole of this book benefits from the new adsorbent designs made possible by the increase in desktop computing and molecular simulation, making Adsorbents useful to both practicing laboratories and graduate programs. Ralph Yang's comprehensive study contributes significantly to the resolution of separation and purification problems by adsorption technologies. See all Editorial Reviews
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