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 ! slavak4609




  28.04.2014 17:03                   e-mail

: ALL.png , , . Akt/mTORC1. , PI3K/Akt .

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(propagating) , - leukemia-propagating cells (LPCs). - (T-ALL), , - LPCs, . T-ALL , , , .

LPCs T-ALL Danio rerio. T-ALL . T-ALL Danio rerio, , . LPCs , . LPCs . , T-ALL, , LPCs . LPCs.

T-ALL . T-ALL LPCs Akt. Akt LPCs , LPCs. Akt T-ALL : LPCs mTORC1.

, T-ALL PTEN Akt. , Akt . , Akt 2206 T-ALL .

, T-ALL , . 2206 - . , , PI3K/Akt T-ALL.


: Blackburn JS, Liu S, Wilder JL, Dobrinski KP, Lobbardi R, Moore FE, Martinez SA, Chen EY, Lee C, Langenau DM. Clonal Evolution Enhances Leukemia-Propagating Cell Frequency in T Cell Acute Lymphoblastic Leukemia through Akt/mTORC1 Pathway Activation. // Cancer Cell. 2014; V. 25: P. 366-378.

: . Danio rerio. LPCs.
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14.05.2014 15:19
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  17.04.2020 19:49                   e-mail
      URL #2

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       25.10.2021 13:25                   e-mail
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  26.06.2022 16:49                   e-mail
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