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картинка: p53_Protocols.gif   Оглавление книги
Methods in Molecular Biology кн.234
Ред. Deb S., Deb S.P.
Humana Press; 2003; 300стр.; ISBN: 1588291065

An indispensable collection of novel techniques that have proven most useful for studying the physiological properties of p53 both in vitro and in vivo. The techniques provide proven solutions to problems in studying the purification, target identification, gene expression, quantitation, interaction, signaling, transactivation, and transrepression of p53. The methods are also useful for delineating the functions of other proteins that may act as tumor or growth suppressors. Each technique includes step-by-step instructions, troubleshooting notes, a theoretical review, and discussion of associated problems that might arise during the course of investigation.
/ Литература,  #22974  /
Область: Молекулярная биология (биохимия, генная инженерия), Биологические методы и инструменты
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            11.06.05  Redactor        комментарии: 0
картинка: Paediatric_and_Neonatal_Critical_Care_Transport.jpg   Оглавление книги
Barry P., Leslie An.
BMJ Publishing Group; 2003; 147стр.; ISBN: 0727917706

ISBN-13: 9780727917706

To buy:


Book Description
Sick babies and children are moved between hospitals for many reasons, often to receive specialist care and treatment not available locally. For the transfer to be safe and effective it is necessary to plan carefully for these occasions, and for the doctors and nurses attending the transport to be able to provide intensive care on the move.The book provides guidance in both of these major areas. The first section - 'Planning for Safe and Effective Transport' - details issues to be considered by senior staff in setting-up or modernising a transport programme. General principles and relevant physiology are outlined, and vehicles and equipment are discussed in depth. The second section - 'Practical Transport Management' - is concerned with different patient groups and key clinical issues. These include the distinctive features of neonatal and paediatric patients, and management of airway, breathing and circulation. Other chapters discuss airborne transport, pharmacology, trauma, and special interventions for transport such as extracorporeal membrane oxygenation and inhaled nitric oxide.

Book Info
Univ. of Leicester, UK. Textbook covers the processes involved in transporting sick children and neonates. Includes the principles of safe transport, transport physiology, ambulance environment, equipment and monitoring, and air transport of critically ill children. British-oriented. For nurses and healthcare workers. Softcover.
/ Книги,  #127755  /
Область: Медицина Экстремальных Состояний
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            26.10.06  musand        комментарии: 1
картинка: Paediatric_Dentistry.jpg   Оглавление книги
(Oxford Medical Publications)
Ред. Welbury R.R., Duggal M.S., Hosey M.T.
Oxford University Press; 2005; 456стр.; ISBN: 0198565836


1. P. H. Gordon: Craniofacial growth and development 2. A. S. Blinkhorn: Introduction to the dental surgery 3. M. L. Hunter and H. D. Rodd: History, examination, risk assessment and treatment planning 4. G. J. Roberts and M. T. Hosey: Management of pain and anxiety 5. J. G. Meechan: Local anaesthesia for children 6. C. Deery and K. J. Toumba: Diagnosis and prevention of dental caries 7. S. A. Fayle: Treatment of dental caries in the pre-school child 8. M. S. Duggal and P. F. Day: Operative treatment of dental caries in the primary dentition 9. J. Smallridge and B. Williams: Operative treatment of dental caries in the young permanent dentition 10. N. M. Kilpatrick and R. R. Welbury: Advanced restorative dentistry 11. P. A. Heasman and P. J. Waterhouse: Periodontal disease in children 12. R. R. Welbury and J. M. Whitworth: Traumatic injuries to the teeth 13. P. J. M. Crawford and M. Aldred: Anomalies of tooth formation and eruption 14. N. E. Carter: The paedo/orthodontic interface 15. J. G. Meechan: Oral pathology and oral surgery 16. M. T. Hosey and R. R. Welbury: Medical disability 17. J. H. Nunn: Childhood disability


From reviews of the previous edition:`This is an excellent book, which I would thoroughly recommend not only for the newly emerging specialists in paediatric dentistry, but for all clinicians that see and treat children. It is a comprehensive book covering all aspects of paediatric dentistry. This latest edition addresses the previous omissions. I find it an easy to read book, which makes it very useful for quick reference in the surgery. I suggest it is well worth the money and should be on everyone's bookshelf.' Dental Update`In a nutshell, it is a textbook that can be wholeheartedly recommended for the bookshelf of anyone interested in paediatric dentistry.' Dental Practice`The book is principally aimed at the undergraduate student and, in this light, both in content and pricing fulfils its role well... I would recommend it to anyone wanting an overview of the subject.' European Journal of Orthodontics`Overall, this is an excellent text for anyone who treats children and it should be on your bookshelves... I would thoroughly recommend it.' Journal of Orthodontics
/ Книги,  #133021  /
Область: Педиатрия, Стоматология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            23.11.06  musand        комментарии: 1
картинка: Paediatric_Neurosurgery.jpg   Оглавление книги
May L.
Whurr Publishers; 2001; 200стр.; ISBN: 1861562241

From publisher

The book is organised to facilitate learning in the rapidly expanding and fascinating area of paediatric neurosurgery; it is presented in a practical way, utilising examples of scenarios and case studies to enhance the understanding of the subject. The essence of family centred care is re-iterated throughout the book, including the continuity of care following discharge from hospital into the community. The importance of the clinical nurse specialist forming the link between hospital and community is included. The book is divided into chapters according to the clinical diagnosis, although clearly there is some overlap (for example the child with a brain tumour and hydrocephalus).

To buy:
/ Книги,  #129939  /
Область: Анатомия, Хирургическая Патология, Педиатрия, Другое в Медицине
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            05.11.06  goddan        комментарии: 1
картинка: Paediatric_Radiography.jpg   Оглавление книги
Hardy M., Boynes S.
Blackwell Science; 2003; 211стр.; ISBN: 0632056312

ISBN-13: 9780632056316

To buy:


Book Info
Univ. of Bradford, UK. Explores radiographic practice within the context of the modern health service and focuses on how knowledge and understanding of pediatric growth, development and illness can inform and influence radiographic procedures. Includes detailed techniques, practice models, and radiation protection. Includes more than 150 radiographs. Softcover.

From the Publisher
Radiography is an integral part of paediatric health care. It is frequently requested to assist in the diagnosis, management and treatment of childhood disease and illness. Accurate interpretation of paediatric radiographs can depend entirely on the quality of images produced by the radiographer, yet there are few books available on this crucial aspect of radiographic practice. Paediatric Radiography fills a gap. It explores radiographic practice within the context of the modern health service and focuses on how our knowledge and understanding of paediatric growth, development and illness can inform and influence radiographic procedures. It includes detailed coverage of specific paediatric techniques and good practice models, including the role of multi-modality imaging, and looks specifically at radiation protection, the chest and upper airways, the abdomen, neonatal radiography, trauma, orthopaedics and non-accidental injury.
/ Книги,  #118834  /
Область: Педиатрия, Диагностика, Лабораторные и Инструментальные Исследования
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            14.09.06  musand        комментарии: 1
картинка: Paediatrics_at_a_Glance.jpg   Оглавление книги
At a Glance
Miall L., Rudolf M., Levene M.I.
Blackwell Science; 2003; 144стр.; ISBN: 0632056436

Book Description
St. James's Univ. Hospital, Leeds, UK. Well-illustrated guide to all aspects of pediatric medicine. Two-page format includes diagrams, summary of differential diagnoses, and details of the relevant history and examination findings. For medical students and those preparing for examinations. Softcover. DNLM: Pediatrics--Handbooks.

Paediatrics at a Glance is a concise, well-illustrated and accessible guide to all aspects of paediatric medicine. Following the easy-to-use At a Glance format, each double-page spread contains a diagram, summarizing the main differential diagnoses for each presenting symptom and how to distinguish them, alongside accompanying text which covers important conditions and management issues in more detail. For each symptom details are given of the relevant history and examination findings to look out for during the consultation. The book is structured into nine sections, which cover the full range of paediatrics. There are distinct sections on development, common symptoms, acute illness, emergencies, the newborn baby, chronic illness and disability. Separate chapters also address evaluating the child, child health surveillance, the child at school, and community and family issues. Written by first-class paediatricians, who are practising clinicians as well as enthusiastic teachers, Paediatrics at a Glance fits the budget and reading time of medical students, pre-registration house officers and general practice trainees. It is ideal as primary or supplementary reading on a lecture-based course and is especially useful for exam preparation. If you are about to go on your paediatric attachment, this book is just what you need! Nursing students, physiotherapists and other health professionals wanting an insight into paediatrics as it is practised will also find this book invaluable.

To buy click here:
barnes & noble
/ Книги,  #110524  /
Область: Педиатрия
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            04.08.06  musand        комментарии: 1
картинка: Pain_Medicine_and_Management_Just_the_Facts.jpg   Оглавление книги
Wallace M.S., Staats P.
McGraw-Hill Professional; 2004; 416стр.; ISBN: 0071411828

ISBN-13: 9780071411820

Book Description
A quick reference to the management of pain for specialists as well as general medical practitioners and residents. Written in a concise bulleted format, the content is limited to only the essential facts necessary for assessment and treatment of common pain conditions and presentations. A perfect review tool for both the anesthesia and pain medicine board exams.

This concise, yet comprehensive review is the perfect tool to prepare for certification, re-certification, CME†or for use as a clinical refresher. Featuring the insights of the world's leading authorities, its highly efficient format conveniently condenses and simplifies only the most important content, for maximum yield and comprehension.
*Perfect for pain medicine and anesthesiology exams†or as a concise clinical consult on the major presentations and interventions in pain
*Standardized, bulleted format highlights and summarizes key concepts, to assure quick absorption of the material and reinforce your understanding of even the most difficult topics
*All key topics covered including physiology, patient assessment, therapeutics and interventional therapies, chronic and acute pain, disability, special techniques, and much more
*Gain easy access to state-of-the-art alternative treatments such as acupuncture and TENS, new treatments for AIDS- and cancer-related pain, and more
*Chapters are logically organized to help focus your study and provide quick access to topics:
*Test Preparation and Planning
*Basic Physiology
*Evaluation of the Pain Patient
*Analgesic Pharmacology
*Acute Pain Management
*Regional Pain
*Chronic Pain Management
*Special Techniques in Pain Management
--This text refers to the Digital edition.

From The Critics
Doody Review Services
Reviewer: Michael F O'Connor, MD (University of Chicago Pritzker School of Medicine)
Description: This is another entry into the growing category of reference books patterned after several popular series in the lay press. Unlike the manuals or handbooks of yesteryear, which were designed to fit (barely) into the pocket of a lab coat, this is a full-size book intended to fit neatly into a pack or pile of papers. It covers the entire range of pain medicine with a large number (70) of brief chapters (370 pages). Most chapters are tersely written, with heavy reliance on the bulleted format.
Purpose: This book is clearly targeted at anesthesia residents and fellows participating in pain management, with explicit recognition of how its content reflects the syllabus for the pain boards. It is also intended to be a concise and highly useful reference for those who are called upon to manage pain less frequently:especially private practitioners and nonanesthesiologists (particularly rehabilitation physicians and neurologists). There has clearly been a need for such a book, and I anticipate that this will become a staple in pain clinics everywhere.
Audience: The list of authors is enormous, and they represent a cross section of the state-of-the-art in pain medicine. The book is clearly oriented to the practice of clinical pain management, with only a brief review of clinically relevant biology in the early portion of the book. Most of the relevant biology is embedded is relevant chapter:the kind of marriage of science and practice that most trainees desire and most quality teachers provide.
Features: The book sections and chapters are organized to mirror clinical pain management. The sections on acute, regional, and chronic pain include chapters that cover every important clinical problem in these domains. Special procedures unique to pain management are similarly covered. Procedures which might be performed by either trainees in pain or by the competent/occasional practitioner are generally well described and covered in appropriate detail, although the quantity and quality of the illustrations is highly variable and generally inferior to better known books in the field. The chapters on disability and return to work are brief and perhaps either too short or too ambitious. The brief index is less than helpful in locating valuable information in the dense text, which will frustrate some users.
Assessment: Residents and fellows may prefer this book to any out there, and are likely to read it before any of the longer, more definitive books on pain. It will be an invaluable reference in any clinic where pain is or might be managed, and an extraordinarily useful reference for practitioners who require a concise manual for pain management.

To buy click here:
/ Книги,  #113704  /
Область: Нехирургическая Патология (Внутренние Болезни), Хирургическая Патология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            17.08.06  musand        комментарии: 1
картинка: Pain.jpg   Оглавление книги
Bountra C., Munglani R., Schmidt W.K.
2003; 968стр.; ISBN: 0824788656

Book Description

This reference presents a detailed overview of approaches and techniques in the management of pain caused by tissue, nerve and central nervous system injuries, categorizing pain into a variety of syndromes and underlying mechanisms to aid the development of interventional pharmacologic measures.

To buy:
/ Книги,  #193933  /
Область: Биология развития и Клеточная биология (иммунология, гистология, нейробиология), Фармакология, Другое в Медицине
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            27.10.07  goddan        комментарии: 1
картинка: Pain_Psychological_Perspectives.jpg   Оглавление книги
Ред. Hadjistavropoulos T., Craig K.D.
Lawrence Erlbaum Assoc.; 2003; 384стр.; ISBN: 0805842993

This invaluable new resource presents a state-of-the-art account of the psychology of pain from leading researchers. It features contributions from clinical, social, and biopsychological perspectives, the latest theories of pain, as well as basic processes and applied issues. The book opens with an introduction to the history of pain theory and the epidemiology of pain. It then explores theoretical work, including the gate control theory/neuromatrix model, as well as biopsychosocial, cognitive/behavioral, and psychodynamic perspectives. Issues, such as the link between psychophysiological processes and consciousness and the communication of pain are examined. Pain over the life span, ethno-cultural, and individual differences are the focus of the next three chapters.

To buy click here:
/ Книги,  #113548  /
Область: Нехирургическая Патология (Внутренние Болезни), Хирургическая Патология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            16.08.06  musand        комментарии: 1

Hammer, Harper D.A.
A Bradford book; 2007; 351стр.

Книга есть на сайте издательства (Wiley Interscience) http://www3.interscience.wiley.com/cgi-bin/bookhome/117351151

Frontmatter (p i-xi)

Chapter 1: Introduction (p 1-7)

Chapter 2: Basic Statistical Methods (p 8-60)

Chapter 3: Introduction to Multivariate Data Analysis (p 61-77)

Chapter 4: Morphometrics (p 78-156)

Chapter 5: Phylogenetic Analysis (p 157-182)

Chapter 6: Paleobiogeography and Paleoecology (p 183-253)
(I am especially interesting in this chapter)

Chapter 7: Time Series Analysis (p 254-278)

Chapter 8: Quantitative Biostratigraphy (p 279-316)

Appendix A: Plotting Techniques (p 317-327)

Appendix B: Mathematical Concepts and Notation (p 328-332)

References (p 333-344)

Index (p 345-351)

/ Книги,  #243224  /
Область: Эволюция, Палеонтология, Таксономия, Антропология
Язык и уровень: Специальный (анг)
Где взять: Эл. версия на сайте издательства
К началу страницы            20.06.08  mhorn        комментарии: 1
картинка: Parasites_of_the_Colder_Climates.jpg   Оглавление книги
Ред. Akuffo H., Ljungstrom I., Linder E., Wahlgren M.
CRC Press; 2002; 384стр.; ISBN: 0415275849

ISBN-13: 9780415275842

To buy:


Book Description
Many texts on parasitology concentrate on tropical parasitic infections, so the reader may think that parasites are not a problem in the north. Parasites of the Colder Climates redresses the balance by focusing on parasites indigenous to cooler climates. A multi-authored text, it provides a comprehensive overview of parasites in these areas and the diseases they cause. Topics include epidemiology, biology and pathogenesis, clinical presentations, laboratory analysis and methods for diagnosis. This text presents diagnostic methods and preventative information for epidemiologists, clinicians and parasitologists and is suitable for researchers, advanced undergraduates and postgraduates.

Book Info
Karolinska Institutet, Sweden. Focuses on the problems of parasites indigenous to the cooler climates of the Northern hemisphere. Provides a comprehensive overview of these parasites and the diseases they cause. Discusses their epidemiology, biology, pathogenesis, clinical presentations, laboratory investigations, and methods for laboratory diagnosis.

From the Publisher
Parasites of the Colder Climates presents a concise single reference of diagnostic methods and preventative information for epidemiologists, clinicians and parasitologists and forms a unique account suitable for researchers, advanced undergraduates and postgraduates.

From The Critics
Doody Review Services

Reviewer: Grace M. Auten, MD (Piedmont Infectious Diseases Consultants, PA)
Description: The editors of this book, from the Swedish Institute for Infectious Disease Control in Stockholm and Olna, have produced a work that focuses on parasites indigenous to northern climates, as well as parasites indigenous to other climates that are found in the north. General epidemiology of northern regions are reviewed by location, followed by epidemiology of specific parasites. Biology, pathogenesis, clinical features, and laboratory methods follow. The concluding chapter is a historical review.
Purpose: The purpose is to correct the impression that parasitic infections are limited to tropical/subtropical areas. This is a worthy goal and this is the first book devoted to the review of parasitic infections indigenous to and found in northern climates.
Audience: The book is targeted to medical students, parasitologists, other scientists, and practitioners who are located in northern climates, as well as the international community. The editors observe that visitors to the cold north are surprised at the extent of the micro-predators and ectoparasites of the region. The knowledgeable and informative authors of individual chapters are associated with medical institutions of higher learning from northern Europe, Russia, Iceland, the Baltic states, and Canada.
Features: Parasitic infections found in northern climates are reviewed. There is distinction of parasites found in the north from parasites found in other geographical areas. For example, HIV-infected individuals rarely have leishmaniasis in northern climates. Uniquely northern parasites such as the northern fowl mite and deer nostril fly are discussed. The fish tapeworm, Diphyllobothrium latum, indigenous to Baltic states and Russia, is meaningfully reviewed. Common diseases with high incidences in the north, such as Lyme Disease in Sweden, are featured. There is overlap between chapters regarding toxoplasmosis and several other parasites. This book, which focuses on northern climates, also overlaps with general parasitology textbooks because of a general review of parasites. The historical review in the last chapter gives the reader a deep appreciation of the contribution to clinical parasitology by famous researchers Carl Linnaeus, Armauer Hansen, Elias Bengtsson and others.
Assessment: The book might be more accurately titled Parasites of Northern Climates: Indigenous Infections and a Perspective on Universally Endemic Parasites as Pertains to the Populations of the North. Neither the colder climates of high altitude nor the southern hemisphere is specifically discussed. As such, the book is a valuable resource to medical students, parasitologists, and practitioners in northern climates, and is an essential addition to a complete parasitology library internationally.
/ Книги,  #115593  /
Область: Инфекционные Болезни, Иммунный Ответ
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            29.08.06  musand        комментарии: 1
картинка: Parenteral_Quality_Control.jpg   Оглавление книги
Drugs and the Pharmaceutical Sciences: a Series of Textbooks and Monographs
Akers M.K., Larrimore D., Guazzo D.
Informa Healthcare; 2002; 408стр.; ISBN: 0824708857

ISBN-13: 9780824708856

To buy:


Book Description
Providing a well-written and easy-to-read review of the subject, this reference describes the most recent breakthroughs in the validation and execution of testing schemes for parenteral quality control. Emphasize testing methodologies for the evaluation of package integrity, finished product contamination, and sterility, the book is a guide to testing and assuring that products for injecting drugs are sterile, free from pyrogenicity, and free from particulate matter. The authors highlight methods that meet US and European standards, explain regulatory requirements and harmonization between various authorities, and review trends and recent developments in technology.

Book Info
Baxter Pharmaceutical Solutions, Bloomington, IN. Text describes the recent advances in the validation and execution of testing schemes for parenteral control. Emphasizes testing methodologies for the evaluation of package integrity, finished product contamination, and sterility. Previous edition: c1993.

From the Publisher
This reference describes the most recent breakthroughs in the validation and execution of testing schemes for parenteral quality control - emphasizing testing methodologies for the evaluation of package integrity, finished product contamination, and sterility.

Akers is joined by Daniel S. Larrimore and Dana Morton Guazzo, all employees of US pharmaceutical companies, to provide quality control practitioners a guide to testing and assuring that products for injecting drugs are sterile, free from pyrogenicity, and free from particulate matter. Focusing on methods that meet US and European standards, they critique the adequacy of current test methods, explain new regulatory requirements and harmonization between various authorities, and review trends and recent developments in technology. The third edition expands the discussion of barrier isolation technology, which has become the standard in sterility testing. No dates are noted for earlier editions. Annotation c. Book News, Inc., Portland, OR

From The Critics
Pharmaceutical Technology

...the author should be congratulated for providing a valuable, well-written, and easy-to-read review of his subject....This book can be recommended with few reservations.

A guide to practices for ensuring that drugs meant for injection are sterile and free from particles and unwanted microbial byproducts; and to the measures that can be taken to verify claims to that effect. With an emphasis on practical advice, describes and analyzes the current US Pharmacopeial testing procedures and requirements; the advantages and limitations of the current compendial testing procedures; and alternatives and emerging trends. Updated from the 1985 first edition to account for recent technologies and regulations. Annotation c. Book News, Inc., Portland, OR (booknews.com)
/ Книги,  #120649  /
Область: Фармацевтическая промышленность, Фармакология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            24.09.06  musand        комментарии: 1
картинка: Parenting_An_Ecological_Perspective_Second_Edition_ed2.jpg   Оглавление книги
Ред. Luster T., Okagaki L.
Lawrence Erlbaum Associates; 2005; 464стр.; ISBN: 0805848061

Book Description

Parenting: An Ecological Perspective was originally created in 1993 to answer questions such as: Why do parents differ markedly in the ways in which they care for their children? What factors contribute to individual differences in parenting behavior? The framework used for addressing these questions is the ecological perspective developed by Urie Bronfenbrenner, who recognized that children's development is influenced by the interactions that they have over time with the people, objects, and symbols in their immediate environment.Luster and Okagaki have updated the original text focusing on parental behavior and also included 6 new chapters covering topics such as:*fathers/gender of parent;*children with special needs;*ethnicity and socioeconomic status; and*parent education.The text summarizes the latest research on factors that influence parenting, with each chapter providing a look at one important influence and the linkages among these various factors. An ecological perspective draws attention to the fact that the lives of parents and children are intertwined, and that understanding factors that influence parents is important for understanding the experiences of children.

To buy:
/ Книги,  #136348  /
Область: Экология и Окружающая среда
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            08.12.06  goddan        комментарии: 1
картинка: Parkinson_s_Disease.jpg   Оглавление книги
Ред. Ebadi M., Pfeiffer R.F.
CRC Press; 2004; 1080стр.; ISBN: 0849315905

ISBN-13: 9780849315909

To buy:


I would recommend it highly to those with a specialist's interest in Parkinson's disease and to more general neurologists who want an accessible, readable guide to diagnosing and treating this disease. New England Journal of Medicine, September 2005A new encyclopedic collection of clinical wisdom…the largest and most comprehensive of several reference books that focus on this illness….masterfully organized. Parkinson's Disease Update, Issue 145, 2005

Book Description
A new optimism that Parkinson's disease can be defeated is energizing the research community. Halting the progression of the disease, restoring function, and even prevention are all realistic goals. This comprehensive volume provides state-of-the-art information on all aspects of Parkinson's disease, including epidemiology, genetics, diagnosis, treatment, and social issues. Novel and attractive models are included to simplify difficult-to-understand concepts. With a focus on therapeutics and written by leaders in the field, Parkinson's Disease emphasizes both the importance of early diagnosis and the search for more effective therapies.
From the Publisher
In this comprehensive volume, leading medical authorities provide state-of-the-art information on all aspects of Parkinson's disease. They cover the historical background, neuropathological and neurophysiological characteristics, epidemiological aspects, clinical features, current treatment approaches, and potential therapeutic methods. Novel models are included to simplify more complex concepts. With its authoritative coverage and clear focus on therapeutics, Parkinson's Disease emphasizes both the importance of early diagnosis and the search for more effective therapies.

The characteristic shaking and rigid muscular movement of what we know as Parkinson's disease (PD) were known long before James Parkinson described the disorder in 1817, according to Ebadi (pharmacology, U. of North Dakota School of Medicine and Health Sciences) and Pfeiffer (neurology, U. of Tennessee Health Science Center). International contributors to the volume's 78 chapters address the neurodegenerative disease's less well-known non-motor symptoms; epidemiologic and clinical considerations; progress in understanding neuropathological and genetic factors in PD; and current and emerging treatment approaches including gene, stem cell, and nonpharmacologic therapies. Lastly, the support/advocacy roles of private nonprofit organizations, e.g., the Michael J. Fox Foundation for Parkinson Research, are discussed. Annotation ©2004 Book News, Inc., Portland, OR
/ Книги,  #119347  /
Область: Психиатрия, Невропатология, Психология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы      Благодарностей за сообщение: 1 // AndriiD       17.09.06  musand        комментарии: 1
картинка: Parkinson_s_Disease_Methods_and_Protocols.gif   Оглавление книги
Methods in Molecular Medicine кн.62
Ред. Mouradian M.M.
Humana Press; 2001; 336стр.; ISBN: 1592591426

Internationally recognized biomedical investigators describe in detail the major techniques employed in molecular and cellular studies of Parkinson's disease and basal ganglia function. Widely varied methods are covered, including genetic analyses, molecular pathogenetic investigations of dopaminergic neuronal degeneration, biochemical studies of nigro-striatal neural circuitry, and molecular therapies, such as gene therapy and neural stem cells. Comprehensive and timely, Parkinson's Disease: Methods and Protocols offers scientists and clinicians interested in Parkinson's and related neurodegenerative disorders the major cutting-edge methods-in a readily reproducible format-needed to effectively exploit the potential of cell and molecular biology for elucidating disease mechanisms and for speeding the emergence of novel and more effective therapeutics.
/ Литература,  #22651  /
Область: Молекулярная биология (биохимия, генная инженерия), Биомедицина и Разработка лекарств, Биологические методы и инструменты
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            10.06.05  Redactor        комментарии: 0
картинка: PARP_as_a_Therapeutic_Target.jpg   Оглавление книги
Ред. Zhang J.
CRC Press; 2002; 360стр.; ISBN: 0849300738

ISBN-13: 9780849300738

To buy:

Book Description
Recent research in cell death mechanism has rekindled interest in PARP's (poly(ADP-ribose)polymerase) intriguing role in necrosis and apoptosis. This book covers the clinical aspects of PARP inhibitors, a promising class of drugs that counteracts the damage done by free radicals. International experts currently working on ways to apply it discuss its therapeutic potential in various forms of ischemia, diabetes, arthritis, inflammatory bowel disease, and septic shock.

Book Info
Provides a comprehensive understanding of how PARP works to aid in the better design of its inhibitors for therapeutic purposes. Covers clinical aspects of this drug that counteract the damage done by free radicals.

From The Critics
Intended for pharmaceutical scientists and biologists, this book presents perspectives of multiple potentials for the clinical utilities of PARP inhibitors. Focusing on the biological activities of PARP inhibition in animal models of disease, the book links basic PARP pathways to its roles in pathogenesis. It covers the clinical aspects of drugs which counteract the damage done by free radicals, and discuss the therapeutic potential in various disease conditions. Annotation c. Book News, Inc., Portland, OR (booknews.com)
/ Книги,  #120648  /
Область: Молекулярная биология (биохимия, генная инженерия), Биомедицина и Разработка лекарств, Фармакология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            24.09.06  musand        комментарии: 1
картинка: Passing_the_General_Surgery_Oral_Board_Exam.jpg   Оглавление книги
Neff M.
Springer-Verlag; 2005; 162стр.; ISBN: 0387260773

ISBN-13: 9780387260778

To buy:


Book Description
Dr. Neff writes in the preface, "I thought about what I had done to prepare for the Exam: two review courses, flashcards, a variety of texts. I realized, however, there is no source of information that tells you what the "wrong" answers are…what are the curveballs likely to be thrown at you during the exam." After realizing that he had done all he could have as a student in preparation for the exam, it became apparent to Dr. Neff that the real problem was that he was merely memorizing material for the exam and not preparing for what will appear. Passing the General Surgery Oral Board Exam offers this to students by not only covering the concepts frequently addressed on the test, but it also includes the "common curveballs and strikeouts" to look out for – the unexpected problem or seemingly benign action (or inaction) that could result in a missed diagnosis or misdiagnosis (and thus in failure to pass the exam).

About the Author
After passing the General Surgery Oral Board Exam on his second attempt, Marc A. Neff, M.D. saw a need for a textbook that would assist students in preparing entirely for this exam. He realized that merely completing a few review classes, and memorizing text was not enough. Students needed a source that will enable them the caliber to become successful on the Oral Exam. To do this, a textbook would provide them with an outline of "what the wrong answers are," and an outline of the common curveballs. This book was written based on the experience of Dr. Neff and that of numerous colleagues interviewed for the project. This fact is what makes it such an incomparable resource. Dr. Neff is a general surgeon at the Crozer Regional Cancer Center, Upland, PA, USA.
/ Книги,  #136211  /
Область: Хирургическая Патология
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            07.12.06  musand        комментарии: 1
картинка: Passion_for_DNA_Genes_Genomes_and_Society_A.jpg
Watson J.D.
Oxford University Press; 2000; ISBN: 0198507313

Jim Watson is one of the world's most famous scientists. A principal architect and visionary of modern biology, a Nobel Prize winner at 34, and best selling author at 40 (The Double Helix), he has been a fearless commentator on the march of DNA science and its impact on society for over twenty years. This sparkling collection was a bestseller in hardcover, and, for the paperback edition, the author has added three newly written essays containing his reflections on the survival value of pursuing happiness, advice for new college graduates, and his thoughts on the completion of a draft of the human genome, a project he initiated over ten years ago.
/ Книги,  #131842  /
Область: Генетика и Селекция
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            20.11.06  musand        комментарии: 1
картинка: Pasteur_s_Quadrant_Basic_Science_and_Technological_Innovation.gif   Оглавление книги
Stokes D.E.
The Brookings Institution; 1997; 196стр.; ISBN: 0815781784

Over fifty years ago,Vannevar Bush released his enormously influential report, Science, the Endless Frontier, which asserted a dichotomy between basic and applied science. This view was at the core of the compact between government and science that led to the golden age of scientific research after World War II--a compact that is currently under severe stress. In this book, Donald Stokes challenges Bush's view and maintains that we can only rebuild the relationship between government and the scientific community when we understand what is wrong with that view.

Stokes begins with an analysis of the goals of understanding and use in scientific research. He recasts the widely accepted view of the tension between understanding and use, citing as a model case the fundamental yet use-inspired studies by which Louis Pasteur laid the foundations of microbiology a century ago. Pasteur worked in the era of the "second industrial revolution," when the relationship between basic science and technological change assumed its modern form. Over the subsequent decades, technology has been increasingly science-based. But science has been increasingly technology-base--with the choice of problems and the conduct of research often inspired by societal needs. An example is the work of the quantum-effects physicists who are probing the phenomena of semiconductors from the time of the transistor's discovery after World War II.

On this revised, interactive view of science and technology, Stokes builds a convincing case that by recognizign the importance of use-inspired basic research we can frame a new compact between science and government. His conclusions have major implications for both the scientific and policy communities and will be of great interest to those in the broader public who are troubled by the current role of basic science in American democracy.
/ Литература,  #22652  /
Область: Научные исследования (другое)
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            10.06.05  Redactor        комментарии: 0
картинка: Patch_Clamping_An_Introductory_Guide_to_Patch_Clamp_Electrophysiology.jpg   Оглавление книги
Molleman A.
John Wiley & Sons; 2002; 186стр.; ISBN: 047148685X

Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology is a concise introduction to the basic principles and practical applications of this important technique. Starting with a review of the history of patch clamping, the text then goes on to cover the fundamentals of the subject, platforms, equipment and environmental control. This self-contained guide provides everything a practising patch clamp electrophysiologist needs to know to master this important technique, including an overview of membrane biophysics, standard experimental design, data analysis and technical concerns.

Aimed at novice and intermediate researchers within neurobiology laboratories, this text will also be of interest to people new to this technique, in universities and research labs as well as research technicians. A useful reference for undergraduates specialising in neurophysiology, neuropharmacology and applied physiology.

  • A self-contained guide introducing basic principles and practical applications
  • A practical approach to the subject and written in an accessible non-technical style
  • Extensive coverage of recording modes, analysis of results and numerous handy hints on how to avoid common pitfalls.

/ Литература,  #22653  /
Область: Молекулярная биология (биохимия, генная инженерия), Биофизика, Физиология (растений и животных), Биологические методы и инструменты
Язык и уровень: Специальный (анг)
Где взять: Было в сети
К началу страницы            10.06.05  Redactor        комментарии: 3
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